Protein Info for Dsui_1606 in Dechlorosoma suillum PS

Annotation: periplasmic serine protease, Do/DeqQ family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 497 signal peptide" amino acids 1 to 34 (34 residues), see Phobius details TIGR02037: peptidase Do" amino acids 70 to 492 (423 residues), 499.2 bits, see alignment E=5.4e-154 PF00089: Trypsin" amino acids 129 to 286 (158 residues), 72.6 bits, see alignment E=1.5e-23 PF13365: Trypsin_2" amino acids 130 to 263 (134 residues), 128.6 bits, see alignment E=1.1e-40 PF00595: PDZ" amino acids 298 to 363 (66 residues), 33.9 bits, see alignment E=1.2e-11 amino acids 410 to 477 (68 residues), 24.6 bits, see alignment E=9.6e-09 PF13180: PDZ_2" amino acids 302 to 388 (87 residues), 59 bits, see alignment E=1.6e-19 amino acids 415 to 494 (80 residues), 30.2 bits, see alignment E=1.6e-10 PF17820: PDZ_6" amino acids 329 to 382 (54 residues), 39.6 bits, see alignment 1.3e-13 amino acids 434 to 485 (52 residues), 47.2 bits, see alignment 5.1e-16

Best Hits

Swiss-Prot: 50% identical to DEGPL_MARMS: Probable periplasmic serine endoprotease DegP-like (Mmwyl1_1102) from Marinomonas sp. (strain MWYL1)

KEGG orthology group: K01362, [EC: 3.4.21.-] (inferred from 62% identity to tmz:Tmz1t_0105)

Predicted SEED Role

"HtrA protease/chaperone protein"

Isozymes

Compare fitness of predicted isozymes for: 3.4.21.-

Use Curated BLAST to search for 3.4.21.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See G8QPT6 at UniProt or InterPro

Protein Sequence (497 amino acids)

>Dsui_1606 periplasmic serine protease, Do/DeqQ family (Dechlorosoma suillum PS)
MTKIPFRPLPFRFSRSVAAFAAGGLLAFVAAQADLSLISRSNAAPATVAAASAAAVPGPA
AGAPLAALPDFSALVEQVGSAVVNISTVTLAKNSNVSGINPNDPFYDFLRRFGIAPGMGS
QQPQESRGIGSGFIVSADGYVLTNAHVVADADEVAVKLTDKREFKAKVVGIDRRSDVALI
KIAASNLPTVRIGSPDRLKVGEWVAAIGAPFGFENSVTAGIVSAKSRALPDETYVPFIQT
DVAINPGNSGGPLFNLKGEVVGINSQIYSRSGGYQGISFAIPIDVAMKVKDQLQKTGKVQ
RGRLGVTMQPVTKELAESFGLAKPVGALVTGVDRSSPADKAGLQPGDVIIALDGVPIEEA
TDLPRKVGDSAPGTKLGLTVLRDGKRLEKQAVLAAMPSETAPQARGESAGGGRVGLAVRS
LSREEAAALGSSGVVVVGVNGPAARAGLQEGDVVLAVNNARVSSPAQLKELLDQAGKRFA
LLIQREDARLYVPVRTD