Protein Info for Dsui_1472 in Dechlorosoma suillum PS

Annotation: deoxynucleoside kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF13238: AAA_18
  • amino acids 16 to 155 (140 residues), 34.2 bits, E=6.6e-12
• PF01712: dNK
  • amino acids 16 to 209 (194 residues), 121.8 bits, E=6.6e-39
• PF13671: AAA_33
  • amino acids 16 to 161 (146 residues), 27.3 bits, E=8.1e-10
• PF02223: Thymidylate_kin
  • amino acids 18 to 178 (161 residues), 35.4 bits, E=1.8e-12

Best Hits

KEGG orthology group: K10353, deoxyadenosine kinase [EC: 2.7.1.76] (inferred from 60% identity to har:HEAR2640)

Predicted SEED Role

"Deoxyadenosine kinase (EC 2.7.1.76) / Deoxyguanosine kinase (EC 2.7.1.113)" in subsystem Purine conversions or PnuC-like transporters (EC 2.7.1.113, EC 2.7.1.76)

MetaCyc Pathways

• purine deoxyribonucleosides salvage (6/6 steps found)

KEGG Metabolic Maps

• Purine metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.1.113 or 2.7.1.76

Sequence Analysis Tools

See G8QNM2 at UniProt or InterPro

Protein Sequence (224 amino acids)

>Dsui_1472 deoxynucleoside kinase (Dechlorosoma suillum PS)
MPGTPARNLLEHARNIVVEGPIGVGKTSLARRLAEHLGQSKECQLLLEQPELNPFLTRFY
QERSRYALQTQLFFLFQRQDQLRDLAQPDIFRQTVVSDFLFEKDPIFARLTLAEDEYKLY
RQIYDTLAPQVVSPDLVIYLQASPENLIARVKKRGLDMERRIGDVYLTQLAESYSRFFYG
YNAAPVMIVNSDRLNFVDQDRDFHLLLERLAAMRGHREYFNRGE