Protein Info for Dsui_1351 in Dechlorosoma suillum PS

Annotation: DNA/RNA helicase, superfamily II

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 641 PF00270: DEAD" amino acids 31 to 196 (166 residues), 171.5 bits, see alignment E=2.7e-54 PF04851: ResIII" amino acids 49 to 190 (142 residues), 22.5 bits, see alignment E=1.9e-08 PF00271: Helicase_C" amino acids 232 to 341 (110 residues), 104.3 bits, see alignment E=9e-34 PF03880: DbpA" amino acids 503 to 572 (70 residues), 72.8 bits, see alignment E=3.8e-24

Best Hits

Predicted SEED Role

"DEAD-box ATP-dependent RNA helicase CshA (EC 3.6.4.13)" (EC 3.6.4.13)

Isozymes

Compare fitness of predicted isozymes for: 3.6.4.13

Use Curated BLAST to search for 3.6.4.13

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See G8QMW1 at UniProt or InterPro

Protein Sequence (641 amino acids)

>Dsui_1351 DNA/RNA helicase, superfamily II (Dechlorosoma suillum PS)
MTSSVDTFAQLGLSEPILQALTDVGYETPSSIQAECIPLLMEGKDLLGMAQTGTGKTAAF
ALPLLQKLDVTQRFPQALVLAPTRELAIQVAEACQKYAKHLPGFHVLPIYGGQSLGIQLK
QLQRGAHVIIGTPGRVMDHLERKSLDLSRLKTLVLDEADEMLRMGFIDDVEWILEHIPAE
RQTALFSATMPEQIRRVAQKYLRDPQEVKIKSATSTVSAIQQRYWQVSGLHKLDALTRIM
EVEDSLDAAIIFVRTKTATEELAQKLEARGYAAAALNGDMNQASRERVIEQLKSGGLDIV
IATDVAARGIDVPRVSHVINYDIPYDVEAYVHRIGRTGRAGRTGTAILFVSPREMRMLRT
IEKVTRQNISPLRLPTKQDVADRRVAQFKQQVIKTLEAGELSFFEEVVTQIEEEANVGAH
EVAAALAFLVQKSRPLLMPEKEVRSFEADSAEGRPERKERFERPERGERFERKERPERGE
RLERTDAKKGKGRDLGNVGNMVRYRIEVGRNQGATPKDIVGCIANEADIQSRYIGHIALF
DEYSTVELPDSLPKDALMLLKEVEIKQCPLLIHRLDGESEVIAPPRRKWGGDVDGNRAPR
GAAPGGKGGFSKPGFGNKKPGGTGGFGGNKPPAKRRAPREG