Protein Info for Dsui_1277 in Dechlorosoma suillum PS

Annotation: glycerol-3-phosphate dehydrogenase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF01210: NAD_Gly3P_dh_N
  • amino acids 2 to 158 (157 residues), 150.3 bits, E=9.1e-48
• PF07479: NAD_Gly3P_dh_C
  • amino acids 178 to 317 (140 residues), 184.5 bits, E=2.4e-58
• PF20618: GPD_NAD_C_bact
  • amino acids 238 to 304 (67 residues), 81.1 bits, E=1.5e-26

Best Hits

Swiss-Prot: 67% identical to GPDA_DECAR: Glycerol-3-phosphate dehydrogenase [NAD(P)+] (gpsA) from Dechloromonas aromatica (strain RCB)

KEGG orthology group: K00057, glycerol-3-phosphate dehydrogenase (NAD(P)+) [EC: 1.1.1.94] (inferred from 68% identity to app:CAP2UW1_1510)

Predicted SEED Role

"Glycerol-3-phosphate dehydrogenase [NAD(P)+] (EC 1.1.1.94)" in subsystem Glycerol and Glycerol-3-phosphate Uptake and Utilization or Glycerolipid and Glycerophospholipid Metabolism in Bacteria (EC 1.1.1.94)

MetaCyc Pathways

• phosphatidylglycerol biosynthesis I (6/6 steps found)
• phosphatidylglycerol biosynthesis II (6/6 steps found)
• superpathway of phospholipid biosynthesis III (E. coli) (10/12 steps found)
• CDP-diacylglycerol biosynthesis I (4/4 steps found)
• CDP-diacylglycerol biosynthesis II (4/4 steps found)
• superpathway of cardiolipin biosynthesis (bacteria) (9/13 steps found)
• glycerol-3-phosphate shuttle (1/2 steps found)
• CDP-diacylglycerol biosynthesis III (3/5 steps found)
• phosphatidate biosynthesis (yeast) (3/5 steps found)
• glucosylglycerol biosynthesis (2/5 steps found)
• 1,3-propanediol biosynthesis (engineered) (4/9 steps found)
• superpathway of phospholipid biosynthesis II (plants) (10/28 steps found)

KEGG Metabolic Maps

• Glycerophospholipid metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.1.1.94

Sequence Analysis Tools

See G8QM99 at UniProt or InterPro

Protein Sequence (331 amino acids)

>Dsui_1277 glycerol-3-phosphate dehydrogenase (Dechlorosoma suillum PS)
MNIAVLGAGAWGTALAIAFAPAHRVRLWSWEQPQAEIMARERANSRYLPGVSFPEGLEVG
SDLAWAAADADLLLVATPLVGLRPTLRSLKAAGLAGRVPVLWACKGLEAGSAKLPHQVVA
EELGADHPCGALSGPSFADEVARQQPTAITLASADGELAARLARQLHTQRLRIYAHDDVV
GVEVGGAVKNVLAIATGIADGLDLGLNARAALVTRGLAEIARLGEALGGRRETFMGLAGM
GDLILTCTGDLSRNRRVGLALGQGKTLAQTLVDLGHVAEGVSTAAEVAGLARRLGIDMPI
TAAVDAVLHHDLPAAEAASQLLSRDPKPEQG