Protein Info for Dsui_0864 in Dechlorosoma suillum PS

Annotation: phosphate regulon sensor kinase PhoR

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 433 transmembrane" amino acids 6 to 27 (22 residues), see Phobius details amino acids 32 to 51 (20 residues), see Phobius details PF11808: PhoR" amino acids 6 to 85 (80 residues), 41.8 bits, see alignment E=2.3e-14 TIGR02966: phosphate regulon sensor kinase PhoR" amino acids 96 to 426 (331 residues), 424.9 bits, see alignment E=9.9e-132 PF00512: HisKA" amino acids 206 to 274 (69 residues), 69.6 bits, see alignment E=3.9e-23 PF13581: HATPase_c_2" amino acids 319 to 404 (86 residues), 28.2 bits, see alignment E=3.2e-10 PF02518: HATPase_c" amino acids 321 to 428 (108 residues), 94.3 bits, see alignment E=1.3e-30

Best Hits

Swiss-Prot: 44% identical to PHOR_KLEPN: Phosphate regulon sensor protein PhoR (phoR) from Klebsiella pneumoniae

KEGG orthology group: K07636, two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC: 2.7.13.3] (inferred from 57% identity to azo:azo0165)

MetaCyc: 44% identical to sensor histidine kinase PhoR (Escherichia coli K-12 substr. MG1655)
Histidine kinase. [EC: 2.7.13.3]

Predicted SEED Role

"Phosphate regulon sensor protein PhoR (SphS) (EC 2.7.13.3)" in subsystem High affinity phosphate transporter and control of PHO regulon or Phosphate metabolism (EC 2.7.13.3)

Isozymes

Compare fitness of predicted isozymes for: 2.7.13.3

Use Curated BLAST to search for 2.7.13.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See G8QIB0 at UniProt or InterPro

Protein Sequence (433 amino acids)

>Dsui_0864 phosphate regulon sensor kinase PhoR (Dechlorosoma suillum PS)
MVKAVWLRAFFFLFLLCAVTGPVWIFVGRQQAWETFCGGLLLYLLYHLWFLSKLMRWLRG
PLDARVPAGWGIWEVAFAGLHRRVRIRLEQQHSLARALERFRLAGEALPDGVVVFNRHRQ
IDGLNAQAAAHFNLNPATDRGQPVTNLIRQPEMVSYLSAGQFDEPLLLQNDLHKGQTLQI
QVIPYGDDQNLLISRDISQLERLENMRRDFVANVSHELKTPLTVVSGFVEMLVDDFDAYP
REDALHYLRLVQEQSGRMQHLIDDLLTLSALETGSLTPLDERVEVPALLASIQQEAQALS
AGRHQISLVCDGPPVLLGCANELRSAFGNLASNAVRYTPDGGRVELIWQRTADGAAFTVA
DSGIGIAPQHIPRLTERFYRVDRSRSRETGGTGLGLAIVKHVLTRHQGRLEVESEAGKGS
RFSACFPALRIPD