Protein Info for Dsui_0496 in Dechlorosoma suillum PS

Annotation: serine/threonine protein kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00069: Pkinase
  • amino acids 18 to 283 (266 residues), 135.1 bits, E=4.8e-43
• PF07714: PK_Tyr_Ser-Thr
  • amino acids 77 to 239 (163 residues), 62.6 bits, E=5.5e-21
• PF03109: ABC1
  • amino acids 106 to 184 (79 residues), 32.5 bits, E=7.6e-12

Best Hits

KEGG orthology group: K00924, [EC: 2.7.1.-] (inferred from 76% identity to dar:Daro_3849)

Predicted SEED Role

"Serine/threonine protein kinase (EC 2.7.11.1)" (EC 2.7.11.1)

KEGG Metabolic Maps

• Lipopolysaccharide biosynthesis
• Nicotinate and nicotinamide metabolism
• Pentose phosphate pathway
• mTOR signaling pathway

Isozymes

Compare fitness of predicted isozymes for: 2.7.1.-, 2.7.11.1

Use Curated BLAST to search for 2.7.1.- or 2.7.11.1

Sequence Analysis Tools

See G8QFA0 at UniProt or InterPro

Protein Sequence (321 amino acids)

>Dsui_0496 serine/threonine protein kinase (Dechlorosoma suillum PS)
MASQANHPLPAGFQLEDYRIEKQISVGGFSIVYLAHDASGKAVAIKEYLPASLALRSEGQ
TKPVISQEHLSAFRYGMKCFFEEGRALAKLNHPNVIQVLNFFRANDTVYMVMEYERGRTL
QEFIQKHHGHIHEKFIRGVFTRMLNGLREVHTHKLLHLDLKPSNIYLRADNTPVLIDFGA
ARQTLHSDTPMLKPMYTPGFASPEHYFKRDELGPWSDIYSVGASMYSCLAGAAPQAADAR
MEKDQLQPASVRWEGQYSDQLLETIDWCLCLNHLYRPQSVFALQKALTEAVDMPAQGASK
AAEKEGWLGHLVGKIKGMTAK