Protein Info for Dsui_0451 in Dechlorosoma suillum PS

Annotation: hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 160 PF02590: SPOUT_MTase" amino acids 1 to 157 (157 residues), 159.5 bits, see alignment E=3.4e-51

Best Hits

Swiss-Prot: 73% identical to RLMH_DECAR: Ribosomal RNA large subunit methyltransferase H (rlmH) from Dechloromonas aromatica (strain RCB)

KEGG orthology group: K00783, hypothetical protein (inferred from 73% identity to dar:Daro_0171)

MetaCyc: 45% identical to 23S rRNA m3psi1915 methyltransferase (Escherichia coli K-12 substr. MG1655)
RXN-11592 [EC: 2.1.1.177]

Predicted SEED Role

"LSU m3Psi1915 methyltransferase RlmH" in subsystem Ribosome biogenesis bacterial

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.1.1.177

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See G8QPK9 at UniProt or InterPro

Protein Sequence (160 amino acids)

>Dsui_0451 hypothetical protein (Dechlorosoma suillum PS)
MKLCIIAVGHRMPDWVAEGCAEYIKRMPREMAVSVVEIKPEPRGSKTREQLLSAEKARIR
AALPGGCRIVALDERGEDLSTVKLAARLEGWMGEGRDIALLIGGADGLDPELKAEAQQNG
GAMLRLSSLTLPHAMARLILCEQLYRAVSVIRNHPYHREG