Protein Info for Dsui_0424 in Dechlorosoma suillum PS

Annotation: phosphoketolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 806 PF09364: XFP_N" amino acids 19 to 381 (363 residues), 538.8 bits, see alignment E=8.6e-166 PF03894: XFP" amino acids 412 to 586 (175 residues), 269.6 bits, see alignment E=1.7e-84 PF09363: XFP_C" amino acids 599 to 802 (204 residues), 282.9 bits, see alignment E=1.9e-88

Best Hits

Swiss-Prot: 67% identical to PHK_SYNP6: Probable phosphoketolase (syc2013_c) from Synechococcus sp. (strain ATCC 27144 / PCC 6301 / SAUG 1402/1)

KEGG orthology group: K01621, phosphoketolase [EC: 4.1.2.9] (inferred from 68% identity to nhl:Nhal_0746)

Predicted SEED Role

"Xylulose-5-phosphate phosphoketolase (EC 4.1.2.9) @ Fructose-6-phosphate phosphoketolase (EC 4.1.2.22)" (EC 4.1.2.22, EC 4.1.2.9)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 4.1.2.22 or 4.1.2.9

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See G8QPI2 at UniProt or InterPro

Protein Sequence (806 amino acids)

>Dsui_0424 phosphoketolase (Dechlorosoma suillum PS)
MSAMPASAAPTPPRATVAIDDAELQQLDAFWRAANYLAGAMIYLQDNPLLRQPLAPEHIK
QRPLGHWGASPGLAFAYAHLTRLIRHHDLDAIFLAGPGHGAPGILGPAWLEGSLGDRQPQ
RGWGLAGLTRFCRDFSFPGGLGSHCTPEVPGSIHEGGELGYSLSHAFGAAFDNPELLVTV
MVGDGEAETGPLATAWHSNKFLNPARDGAVLPILHLNGYKIANPTILARIPREELLALFT
GYGWAPKIVEGHEPAAMHRAMAAAMDECLAEIRAIQQAARSGKGPVQRPRWPMIVLVSPK
GWTGPRQADGHQVEGTWRAHQVPLADPRNNAENRRLLQEWLQSYRPQELFTEDGEPAPLL
LDFAPRGRRRLGANPHANGGLLRLPLDRPDWRQQAVTFAAPGSRRHSNTDPLGRHLGQIM
QKNPSNFRLFGPDETASNKLGAVFEVTGKAWLGKSCPEDADGGHLAADGRVMEMLSEHTL
EGWLEGYLLTGRYGLLSTYEAFAHVIDSMFNQHAKWLEMCRDVPWRAPVGALNLLITSTV
WRQDHNGFTHQDPGFLDLVVNKSPAVTRIYLPPDANCLLAVADRCLGETDVINVIVADKQ
AHLQYLEAEAAALHCARGIGLWDWASSDDEAGTEPEVVLASCGDVATQEALAAAELLYRH
FPDLKLRFVNVVDLFTLTPPEEHPHGISERDWTGLFTADKPIVFNFHGYPWLIHRLAYRR
PNHANLHVRGYKERGSICTPLELAMDNQIDRYSLAIDVIDRVPRLAVAGAHVKQALEQKQ
QQCRAHAHRHGVDPEEINTWTWGGQP