Protein Info for Dsui_0421 in Dechlorosoma suillum PS

Annotation: carbonic anhydrase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF16747: Adhesin_E
  • amino acids 49 to 155 (107 residues), 40 bits, E=4e-14
• PF00194: Carb_anhydrase
  • amino acids 264 to 477 (214 residues), 141.4 bits, E=4.2e-45

Best Hits

KEGG orthology group: K01674, carbonic anhydrase [EC: 4.2.1.1] (inferred from 59% identity to app:CAP2UW1_1607)

Predicted SEED Role

"Carbonic anhydrase (EC 4.2.1.1)" in subsystem Carboxysome or Cyanate hydrolysis (EC 4.2.1.1)

MetaCyc Pathways

• CO₂ fixation into oxaloacetate (anaplerotic) (2/2 steps found)
• cyanate degradation (2/3 steps found)
• C4 photosynthetic carbon assimilation cycle, NAD-ME type (7/11 steps found)
• C4 photosynthetic carbon assimilation cycle, NADP-ME type (4/7 steps found)
• C4 photosynthetic carbon assimilation cycle, PEPCK type (8/14 steps found)
• 3-hydroxypropanoate cycle (7/13 steps found)
• 3-hydroxypropanoate/4-hydroxybutanate cycle (10/18 steps found)
• gluconeogenesis II (Methanobacterium thermoautotrophicum) (8/18 steps found)
• glyoxylate assimilation (4/13 steps found)
• superpathway of the 3-hydroxypropanoate cycle (7/18 steps found)
• Methanobacterium thermoautotrophicum biosynthetic metabolism (20/56 steps found)

KEGG Metabolic Maps

• Nitrogen metabolism

Isozymes

Compare fitness of predicted isozymes for: 4.2.1.1

Use Curated BLAST to search for 4.2.1.1

Sequence Analysis Tools

See G8QPH9 at UniProt or InterPro

Protein Sequence (478 amino acids)

>Dsui_0421 carbonic anhydrase (Dechlorosoma suillum PS)
MPALETNPISAPASLTRGALTTALLLTAGLLQAAPSAAPTKVGDDGRTWQAISTEPGKRI
EVDRASIKRDESGKVSAWGRIVLEKDLPDAQSASNYRSIEALGRYDCSNRTYATLKRVYV
KASGELLREEEIKVATDMPVRANTLDDKLLRDICRPTTAADMRKLTQATVAKANVAAEEL
KKANEEMVKKAVQRESTQAPTPVKSLEHMEIQKPQAAPAYVPRPAPYTAAAPRAAKPRPA
AKPEGLEGAEQHHAIHWSYEGEGGPDFWGRLKPDFATCDKGRRQSPIDIWDGIRVDLPPI
EFSYRPTRFRLVDNGHTLQASFGHGSLTHLGKTYDLVQVHFHRPSEERVNGKAFDMVAHM
VHRSDDNQLAVVAVLLEKGAQEHPVIQTLWNYIPLEKNQEVLPPDAAVDLNQLLPEKRGY
YTYMGSLTTPPCSEGVLWLVMQQPVQVSAQQIAIFSRLYRNNARPVQPSNGRLIKESR