Protein Info for Dsui_0136 in Dechlorosoma suillum PS

Annotation: histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 537 transmembrane" amino acids 22 to 40 (19 residues), see Phobius details amino acids 54 to 76 (23 residues), see Phobius details amino acids 84 to 101 (18 residues), see Phobius details amino acids 105 to 123 (19 residues), see Phobius details amino acids 129 to 150 (22 residues), see Phobius details amino acids 157 to 179 (23 residues), see Phobius details PF00512: HisKA" amino acids 317 to 380 (64 residues), 59.4 bits, see alignment E=2.9e-20 PF02518: HATPase_c" amino acids 424 to 527 (104 residues), 86.9 bits, see alignment E=1.3e-28

Best Hits

KEGG orthology group: K02668, two-component system, NtrC family, sensor histidine kinase PilS [EC: 2.7.13.3] (inferred from 58% identity to app:CAP2UW1_0767)

Predicted SEED Role

No annotation

Isozymes

Compare fitness of predicted isozymes for: 2.7.13.3

Use Curated BLAST to search for 2.7.13.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See G8QM43 at UniProt or InterPro

Protein Sequence (537 amino acids)

>Dsui_0136 histidine kinase (Dechlorosoma suillum PS)
MSFLNVPPVEVSEAHWKSLRYFNFYRLVAAFLLYGAAYLHPSSFELVPATDQSLYTWTAF
VYCLATACSVLLLAFWRRHFNLQLSGQVLLDVVALTVLMHASGGLRGGLGAMLLVSLAGA
GLVGQGRLVLFYAALATLSMLFQQLLLALSSEFDPSAFFQVGLLGAGFFTSAISARLLAR
RVVANEELARKRGEALANQVCVSQRVIEEMQDGVLLVSPLGEVHLHNPRAEALLGLTAGE
AGNLERCSPALEGHFLRWRRREGSKDESGLVFHVPRNGKQLFARFLETPSSAGDTLILLE
DMDRLREESRQMKLAALGRLTANIAHEIRNPLSAISHAGELLREDADPKGGDARLVRIIL
DNTQRLERIVRDVLELGRRDRCHPESIDLNAALAAYLDELQSKAEAAPGVLCLEGLAGAE
LEFDRTHLHQVLWNLLSNALRHSRQQPGSVQLRVAYGNGGMVELHVEDDGPGIPEAIREQ
VFEPFFTTHGKGTGLGLHIARELCEANGAQLELLSESRAGGAHFRITGRRGHGSGQK