Protein Info for Dsui_0120 in Dechlorosoma suillum PS

Annotation: peptide chain release factor 1

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 365 TIGR00019: peptide chain release factor 1" amino acids 1 to 362 (362 residues), 536.3 bits, see alignment E=1.6e-165 PF03462: PCRF" amino acids 13 to 207 (195 residues), 249.8 bits, see alignment E=1.9e-78 PF00472: RF-1" amino acids 218 to 325 (108 residues), 144.8 bits, see alignment E=1.1e-46

Best Hits

Swiss-Prot: 80% identical to RF1_DECAR: Peptide chain release factor 1 (prfA) from Dechloromonas aromatica (strain RCB)

KEGG orthology group: K02835, peptide chain release factor 1 (inferred from 80% identity to dar:Daro_3687)

Predicted SEED Role

"Peptide chain release factor 1" in subsystem LMPTP YwlE cluster

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See G8QM27 at UniProt or InterPro

Protein Sequence (365 amino acids)

>Dsui_0120 peptide chain release factor 1 (Dechlorosoma suillum PS)
MKPSIREKLDQLTRRLEEVDALLSSEEAAKDMDQFRKLSKERAELEPVVSLYGAFRQAEA
DLAAAQEMLADPDMKELAEEEVEAAKARLPELELDLQKLLLPRDPNDERNIFLEIRAGTG
GDESALFAADLFRMYSRYAERQRWQVEVVSANESDLGGYKEVIVRIAGNAAGLGAYSKLK
FESGGHRVQRVPATETQGRIHTSACTVAVMPEVDEVADVELNPADLRIDTYRASGAGGQH
INKTDSAVRVTHLPTGIVAECQDGRSQHANKASALKVLAARIKDVQVREQQAKEAATRKS
LVGSGDRSERIRTYNFPQGRITDHRINLTLYKIDQIMDGDLEELTGALLAEHQAEQLAAL
AEEQG