Protein Info for CSW01_19595 in Vibrio cholerae E7946 ATCC 55056

Annotation: DNA-binding response regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 218 PF00072: Response_reg" amino acids 4 to 112 (109 residues), 93.7 bits, see alignment E=8.3e-31 PF00486: Trans_reg_C" amino acids 146 to 215 (70 residues), 74.3 bits, see alignment E=6.5e-25

Best Hits

Swiss-Prot: 44% identical to QSEB_ECOLI: Transcriptional regulatory protein QseB (qseB) from Escherichia coli (strain K12)

KEGG orthology group: K02483, two-component system, OmpR family, response regulator (inferred from 100% identity to vch:VCA1105)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (218 amino acids)

>CSW01_19595 DNA-binding response regulator (Vibrio cholerae E7946 ATCC 55056)
MRLLLVEDDTLLGESMQVALSRQGYTVDWLERGGGVVTALKTEQFTALILDLTLPDMDGL
EVLRQIRRAGYTLPVMILTARDDISDRVKGLDGGADEYIGKPFALEELLARLRLIIRRSS
GSAEELISVGELDLSLSKQEIYYAQQALKLTRNEYKILASLMTQAGRVMSKELLQQALHG
WDEGSSDNAIEVHIHNLRKKLPDNLVKNVRGVGYMIEK