Protein Info for CSW01_19585 in Vibrio cholerae E7946 ATCC 55056

Annotation: phosphoethanolamine transferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 transmembrane" amino acids 12 to 31 (20 residues), see Phobius details amino acids 49 to 67 (19 residues), see Phobius details amino acids 79 to 100 (22 residues), see Phobius details amino acids 120 to 142 (23 residues), see Phobius details amino acids 159 to 177 (19 residues), see Phobius details PF08019: EptA_B_N" amino acids 60 to 211 (152 residues), 161.9 bits, see alignment E=1.1e-51 PF00884: Sulfatase" amino acids 242 to 530 (289 residues), 231.7 bits, see alignment E=1.2e-72

Best Hits

Swiss-Prot: 39% identical to EPTA_ECOLI: Phosphoethanolamine transferase EptA (eptA) from Escherichia coli (strain K12)

KEGG orthology group: K03760, phosphoethanolamine transferase (inferred from 100% identity to vch:VCA1102)

MetaCyc: 39% identical to phosphoethanolamine transferase EptA (Escherichia coli K-12 substr. MG1655)
RXN-14379 [EC: 2.7.8.43]

Predicted SEED Role

"putative membrane protein"

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.8.43

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (550 amino acids)

>CSW01_19585 phosphoethanolamine transferase (Vibrio cholerae E7946 ATCC 55056)
MVIMPTFNIKPFSYLQLVFLLAAYFALPLNLPVYAQLAHIFNQSTSLDWGFALSIPLFFL
FALNFIFQIFSWPYLFKPFFAVLLVLSALISFAGFQYGVIVDQDMLVNVLETDRGEAGSY
LTIYSVLWLLGFGLVPALALLFTPIRPEKSALRFLMKKGLSMLVSVVVIGVIAGLYYQNY
SSVGRNNSSLKKMIIPTHFLYSSFGLVKQRYFTEPMVYQEIGQDAQQKPSAVRQATQKPT
LVFFVLGETARVQNYQYLGYPRDTNAYTAPFQPIFFKDVASCGTATAVSVPCMFSNMNRQ
NFDRSRADNQDNVLDILQRAGISLLWKENDGGDKNVAKNIPLKELARDNREGICDGDTCY
DIAMLENLDQEIATQQGNRMIFMHFIGSHGPTYFKRYPKEMAVYQPDCPRADIENCSVEQ
IVNTYDNTIRYSDYVMSQLLAKLDSLQDRYNTALIYISDHGESLGENGLFLHGMPYSLAP
EYQTRVPLLIWMSSGFSQSKGIDVECLRSNSELPYAHQNLFHSLLGVMDVSTKAYQANLD
LFAKCRTSQS