Protein Info for CSW01_19570 in Vibrio cholerae E7946 ATCC 55056

Annotation: ABC transporter permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 318 transmembrane" amino acids 12 to 30 (19 residues), see Phobius details amino acids 104 to 125 (22 residues), see Phobius details amino acids 138 to 164 (27 residues), see Phobius details amino acids 175 to 193 (19 residues), see Phobius details amino acids 232 to 257 (26 residues), see Phobius details amino acids 281 to 303 (23 residues), see Phobius details PF19300: BPD_transp_1_N" amino acids 1 to 78 (78 residues), 24.4 bits, see alignment E=2.8e-09 PF00528: BPD_transp_1" amino acids 118 to 309 (192 residues), 140.4 bits, see alignment E=5.7e-45

Best Hits

KEGG orthology group: K02033, peptide/nickel transport system permease protein (inferred from 100% identity to vco:VC0395_0144)

Predicted SEED Role

"ABC transporter, permease protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (318 amino acids)

>CSW01_19570 ABC transporter permease (Vibrio cholerae E7946 ATCC 55056)
MTKILVHRFYQALFVAWSVGTLTFILMRFIPGDVAYRIAAGRYGYDYVNADAALAVRAEL
GLDRSAFELYLQWLWDLLHLNLGHSLVSSEPVIHAIMHNLGHSLLLAGAATLLSLFIAIP
IGVYCGKRTDRWADNLALLTSIMIKAQPVFLIGLGLVILFALQLNWLPVAGFGHPKFLIL
PALALALGMAAMSSRMIRNATAQVLQSPYYAFARLKGLNHEQAFTRHAQRNIALPVMAFV
GIQAVSLVEGIVMIESLFSWPGVGHALSHAIFQRDIPMIQGSALVMGLLFVALNTLVDLV
QYALDPRLRLSRHVQPEA