Protein Info for CSW01_18915 in Vibrio cholerae E7946 ATCC 55056

Annotation: DUF3612 domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 505 PF01381: HTH_3" amino acids 46 to 79 (34 residues), 29.4 bits, see alignment (E = 1e-10) PF12268: DUF3612" amino acids 327 to 501 (175 residues), 342.2 bits, see alignment E=1.2e-106

Best Hits

KEGG orthology group: None (inferred from 100% identity to vcm:VCM66_A0918)

Predicted SEED Role

"Predicted transcriptional regulator"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (505 amino acids)

>CSW01_18915 DUF3612 domain-containing protein (Vibrio cholerae E7946 ATCC 55056)
MSVSKSLVRQSHFLGTKVRNLRKRNHLTMEDLSARCIRVSPEYAPSVSYLSMIERGKRVP
SVEMLEVIAEVFQKDPIWFLDDEPEQIDITPEKGNRGGISGMALEPSFLFSNDILQIAIP
EMLSQTGITGRQFAHLLIRAHQESLQNHFPDLERAAEEVGLKRLNLSVTDLLDIAKGLGL
DVRWVKRTPHDVTDELGVSAKQLVTSFFEPPGRIYLNEILREYPTRLKYDLAVYIGHNVL
HNKDGLKSVLSVGHTQGWDEMVETSPSSELNSQDILQAWRDFESSFFAGALLCPKVPFRQ
LLDRNGYEISVHQKAGVSPSVAMRRMTVVSPYPHWHYFDAYGEGKLKAVYRGNGIPLPWG
NMRKVNDPCQHWAVFRRLSQPQQGSSAQISILTVGDEPRIYCCESLNVVDPAGNNRVLCA
GIDLNPAINAQGGDALAIAQELKMSCVQKGGTTAIPAPIKRDLRTIAKILNINWVERGIE
NEARLICSRGAVCPRKPRCYGECGE