Protein Info for CSW01_18865 in Vibrio cholerae E7946 ATCC 55056

Annotation: spermidine acetyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 173 PF13302: Acetyltransf_3" amino acids 5 to 140 (136 residues), 72.1 bits, see alignment E=2.8e-23 PF13420: Acetyltransf_4" amino acids 7 to 157 (151 residues), 48.6 bits, see alignment E=3.4e-16 PF00583: Acetyltransf_1" amino acids 31 to 139 (109 residues), 71.6 bits, see alignment E=2.5e-23 PF13673: Acetyltransf_10" amino acids 41 to 144 (104 residues), 40.5 bits, see alignment E=8.9e-14 PF13508: Acetyltransf_7" amino acids 58 to 141 (84 residues), 42.9 bits, see alignment E=1.8e-14 PF08445: FR47" amino acids 85 to 141 (57 residues), 22.7 bits, see alignment E=2.8e-08

Best Hits

Swiss-Prot: 100% identical to ATDA_VIBCH: Spermidine N(1)-acetyltransferase (speG) from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)

KEGG orthology group: K00657, diamine N-acetyltransferase [EC: 2.3.1.57] (inferred from 100% identity to vcm:VCM66_A0907)

MetaCyc: 61% identical to spermidine N-acetyltransferase (Escherichia coli K-12 substr. MG1655)
Diamine N-acetyltransferase. [EC: 2.3.1.57]; 2.3.1.57 [EC: 2.3.1.57]; 2.3.1.57 [EC: 2.3.1.57]

Predicted SEED Role

"Spermidine N1-acetyltransferase (EC 2.3.1.57)" in subsystem Polyamine Metabolism (EC 2.3.1.57)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.3.1.57

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (173 amino acids)

>CSW01_18865 spermidine acetyltransferase (Vibrio cholerae E7946 ATCC 55056)
MNSQLTLRALERGDLRFIHNLNNNRNIMSYWFEEPYESFDELEELYNKHIHDNAERRFVV
EDAQKNLIGLVELIEINYIHRSAEFQIIIAPEHQGKGFARTLINRALDYSFTILNLHKIY
LHVAVENPKAVHLYEECGFVEEGHLVEEFFINGRYQDVKRMYILQSKYLNRSE