Protein Info for CSW01_18600 in Vibrio cholerae E7946 ATCC 55056

Annotation: PepSY domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 470 transmembrane" amino acids 25 to 49 (25 residues), see Phobius details amino acids 154 to 175 (22 residues), see Phobius details amino acids 205 to 227 (23 residues), see Phobius details amino acids 385 to 406 (22 residues), see Phobius details amino acids 426 to 455 (30 residues), see Phobius details PF03929: PepSY_TM" amino acids 23 to 407 (385 residues), 223.5 bits, see alignment E=5.5e-70

Best Hits

KEGG orthology group: None (inferred from 100% identity to vcj:VCD_000440)

Predicted SEED Role

"Uncharacterized iron-regulated membrane protein; Iron-uptake factor PiuB"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (470 amino acids)

>CSW01_18600 PepSY domain-containing protein (Vibrio cholerae E7946 ATCC 55056)
MSTVTTPQPTAAARRKTLYFLTWRWHFYAGLFVVPFMLMLALTGLVMLFDDEIEQARYAE
VLNVTPQAQVMPVSQQLAAVQKAYPEAQVTQFIPAHQPDLANRFSVLFSDGSTQFVTVSP
YSAVVLGAIDRSESWYEWANSIHGTLLIGDWGDYLIEVAASLGMILLVSGIYLWLPLDNA
RKAGFLKIRVGSGARIFWRDLHANLGGMLSLVLLFFLISGLSWAGIWGGKLVQAWNTFPT
YYTWGEKPQSVLTHADLNHGSEKEMPWNLEQTPVPQSHHHGGEHEMVAVNPQFGIDQVIA
QAKALGFTQYRVAFPRGETGVYTVSANTMAGDIVDPRDDRTAHFDQYSGALLTEVTWQDY
SPFAKAMAAGISLHQGDLSVWNKIANVLFCLAFILISVTGVVMWWLRRPTGQARLGVPPR
FEQDGVWKAGLATLLVIGVAFPLAGATIVLALLLDGLLVSRIAKLKIAFS