Protein Info for CSW01_18480 in Vibrio cholerae E7946 ATCC 55056

Annotation: PLP-dependent aminotransferase family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 473 PF00392: GntR" amino acids 7 to 67 (61 residues), 31.9 bits, see alignment E=8.5e-12 PF00155: Aminotran_1_2" amino acids 136 to 461 (326 residues), 97.6 bits, see alignment E=8.9e-32

Best Hits

Swiss-Prot: 50% identical to YDCR_ECOLI: Uncharacterized HTH-type transcriptional regulator YdcR (ydcR) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 100% identity to vcm:VCM66_A0830)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (473 amino acids)

>CSW01_18480 PLP-dependent aminotransferase family protein (Vibrio cholerae E7946 ATCC 55056)
MMKKSQVLANTIKSQIEQNIWLSGEKIPSIRSTCKRYKLSIETVLQAYQQLEDQGYIRAK
AKSGYVVLPRRNTLFAGNLSAKVIKPYPVKISDLLYDVLQRAKDPEIIPFSSAFPDPALF
PHQALSRSLANASRQMLGSCMLTNLPPGSQTLRRQIAQRYQKSGLNVLPDDIVITSGAME
ALNLCLQSCTKPGDLVAIEYPAFYGVLQAIERLNLTAVEIPTDPRDGIDLDVLASVFSSM
DIKACWFMTESQNPLGYSMSETNKQRLAELVNHYQIPMIEDDVYRELGIGNPSSLPAKAY
DKVGNILLCGSFSKSLSPGFRIGWVVAGERALNIQRLQHLSTLSSSIPIQLGLSHYLTFY
NFDHHLKKLRKLLNERKKAHAELLRTYLPHNTKIHLNNGGYFIWVELPQTIYAETLYEQA
LEHNIAIAPGILFSSDKRFSHHIRLNCSYACDERIEQAIQTLGQLIHTMEINR