Protein Info for CSW01_18275 in Vibrio cholerae E7946 ATCC 55056
Annotation: diaminobutyrate--2-oxoglutarate transaminase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 100% identical to ECTB_VIBCH: Diaminobutyrate--2-oxoglutarate transaminase (ectB) from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
KEGG orthology group: K00836, diaminobutyrate-2-oxoglutarate transaminase [EC: 2.6.1.76] (inferred from 100% identity to vcj:VCD_000500)Predicted SEED Role
"Diaminobutyrate-pyruvate aminotransferase (EC 2.6.1.46)" in subsystem Ectoine biosynthesis and regulation (EC 2.6.1.46)
MetaCyc Pathways
- norspermidine biosynthesis (6/6 steps found)
- ectoine biosynthesis (5/5 steps found)
- superpathway of polyamine biosynthesis III (7/8 steps found)
- ectoine degradation (1/4 steps found)
- rhizobactin 1021 biosynthesis (2/7 steps found)
- baumannoferrin biosynthesis (2/11 steps found)
- pyoverdine I biosynthesis (2/11 steps found)
KEGG Metabolic Maps
Isozymes
Compare fitness of predicted isozymes for: 2.6.1.76
Use Curated BLAST to search for 2.6.1.46 or 2.6.1.76
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Compare to protein structures
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (421 amino acids)
>CSW01_18275 diaminobutyrate--2-oxoglutarate transaminase (Vibrio cholerae E7946 ATCC 55056) MDIFKHHESQVQSYANHFPVLFGTAKGSWLYSQQGDAYLDFLSGAGALNYGHNNAVLKQA LLEYIERDGLTHGLDMHSEAKAHFIQALQTHILEPRGLNYKLQFTGPTGTNAVEAALKLA RKVTGRHNVVTFTNGFHGCSLGALAATGNQHHRQGAGLALSGVYRVPYDGYAGVDGLTLF ETMLQDNSSGLDKPAAVLLETVQGEGGLNVASDAWLQRVQAICRAQQILLIVDDIQAGCG RTGTFFSFEPSGIEPDMVTLSKSLSGYGLPMALVLFKPEWDQWKPGEHNGTFRGNNHAFV TATRALEAYWANQDFQTHIAARSEQVTQALLQCLSRYPTLFSGLKGRGLMQGLACHNGDI ARDIAALCFQKGLIIETAGAEDEVLKVFCPLTITEADLAHGLTIIERSAARIAPRGLQQA S