Protein Info for CSW01_18035 in Vibrio cholerae E7946 ATCC 55056

Annotation: tyrosine transporter TyrP

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 signal peptide" amino acids 1 to 11 (11 residues), see Phobius details amino acids 28 to 30 (3 residues), see Phobius details transmembrane" amino acids 12 to 27 (16 residues), see Phobius details amino acids 39 to 60 (22 residues), see Phobius details amino acids 82 to 102 (21 residues), see Phobius details amino acids 122 to 143 (22 residues), see Phobius details amino acids 150 to 170 (21 residues), see Phobius details amino acids 182 to 207 (26 residues), see Phobius details amino acids 218 to 241 (24 residues), see Phobius details amino acids 271 to 294 (24 residues), see Phobius details amino acids 308 to 327 (20 residues), see Phobius details amino acids 333 to 353 (21 residues), see Phobius details amino acids 374 to 397 (24 residues), see Phobius details PF03222: Trp_Tyr_perm" amino acids 3 to 385 (383 residues), 377.4 bits, see alignment E=1.4e-116 PF01490: Aa_trans" amino acids 6 to 232 (227 residues), 35.7 bits, see alignment E=6.3e-13 PF13520: AA_permease_2" amino acids 6 to 384 (379 residues), 28.3 bits, see alignment E=1.3e-10 TIGR00837: aromatic amino acid transport protein" amino acids 8 to 376 (369 residues), 373.1 bits, see alignment E=9.8e-116

Best Hits

Swiss-Prot: 49% identical to TYRP_SHIFL: Tyrosine-specific transport protein (tyrP) from Shigella flexneri

KEGG orthology group: K03834, tyrosine-specific transport protein (inferred from 100% identity to vcj:VCD_000549)

Predicted SEED Role

"Tyrosine-specific transport protein" in subsystem ZZ gjo need homes

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (400 amino acids)

>CSW01_18035 tyrosine transporter TyrP (Vibrio cholerae E7946 ATCC 55056)
MTQSKLLGSTLIIAGTTIGAGMLALPLASAGIGFSTSLMIMLGLWMLMAFTALLMVEIHQ
YADKEATLHTLAKQILGDKGKWVATFAMLFLFYSLCAAYIAGGGAQFTQRITDFTGVNVE
SSSGTLLFTLIVALVVTVGTGTVDRVNRVLFAGKMIAMVAVLFFLAPNVSQSYLLSMPIQ
QGLIVAAIPVIFTSFGFHGSIPAIVNYLDGDTPALRKAILIGSAIPLVIYIFWQLVTLGV
VSQSALLDNMGLTALIGVLSTTVHQSNLGNIIGVFADLALLTSFLGVSLGLFEFMGDSLR
NQQGKMNRPLASVVTFLPPLIFALFYPQGFIMALGYAAIALAILAIFLPLVMVIKVRQQA
TEQHYQVTGGNGALLVTGLVGLLIIGAQLLITLGILPALG