Protein Info for CSW01_17805 in Vibrio cholerae E7946 ATCC 55056

Annotation: molybdate ABC transporter substrate-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 254 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details PF13531: SBP_bac_11" amino acids 26 to 250 (225 residues), 178.5 bits, see alignment E=1.8e-56 TIGR01256: molybdate ABC transporter, periplasmic molybdate-binding protein" amino acids 31 to 248 (218 residues), 202.2 bits, see alignment E=5.1e-64 PF01547: SBP_bac_1" amino acids 31 to 242 (212 residues), 79.5 bits, see alignment E=4.6e-26

Best Hits

Swiss-Prot: 44% identical to MODA_HAEIN: Molybdate-binding protein ModA (modA) from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)

KEGG orthology group: K02020, molybdate transport system substrate-binding protein (inferred from 100% identity to vcm:VCM66_A0684)

MetaCyc: 45% identical to molybdate ABC transporter periplasmic binding protein (Escherichia coli K-12 substr. MG1655)
ABC-19-RXN [EC: 7.3.2.5]

Predicted SEED Role

"Molybdenum ABC transporter, periplasmic molybdenum-binding protein ModA (TC 3.A.1.8.1)" in subsystem Molybdenum cofactor biosynthesis or Transport of Molybdenum (TC 3.A.1.8.1)

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.3.2.5

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (254 amino acids)

>CSW01_17805 molybdate ABC transporter substrate-binding protein (Vibrio cholerae E7946 ATCC 55056)
MPMLTRILLLLCVALNAPLASAKETLHIYAASSMTNAVNALVADYSQQHDVKLVTVYGGS
SSLARQIEAGAPADLFISANEEWANYLVEKGLVKPNKVVTLAANSLVLIRPTAQPVASFE
LQDAAAWQTALADSRLAVAQVDAVPAGMYAKQALQHAGVWPELESRLAQTNNVRLALALV
ERGESPLGIVYKTDALLSDKVTIVTAFSAQSHQPIRYPLAQLNDKAASAEWVAYLRSDAA
QQILQRFGFESVSE