Protein Info for CSW01_17795 in Vibrio cholerae E7946 ATCC 55056

Annotation: molybdenum import ATP-binding protein ModC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 366 TIGR02142: molybdate ABC transporter, ATP-binding protein" amino acids 4 to 357 (354 residues), 534.8 bits, see alignment E=5.5e-165 PF00005: ABC_tran" amino acids 18 to 159 (142 residues), 109.5 bits, see alignment E=2.1e-35 PF03459: TOBE" amino acids 293 to 357 (65 residues), 61.3 bits, see alignment E=8.4e-21

Best Hits

Swiss-Prot: 100% identical to MODC_VIBCH: Molybdenum import ATP-binding protein ModC (modC) from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)

KEGG orthology group: K02017, molybdate transport system ATP-binding protein [EC: 3.6.3.29] (inferred from 100% identity to vcj:VCD_000595)

MetaCyc: 52% identical to molybdate ABC transporter ATP binding subunit (Escherichia coli K-12 substr. MG1655)
ABC-19-RXN [EC: 7.3.2.5]

Predicted SEED Role

"Molybdenum transport ATP-binding protein ModC (TC 3.A.1.8.1)" in subsystem Molybdenum cofactor biosynthesis or Transport of Molybdenum (TC 3.A.1.8.1)

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.6.3.29 or 7.3.2.5

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (366 amino acids)

>CSW01_17795 molybdenum import ATP-binding protein ModC (Vibrio cholerae E7946 ATCC 55056)
MSEVILQLQKRLGETQLDVDLRLPAVGICAIFGRSGAGKTSLINLISGLTTPDVGEIHLA
GRTLFSSSQGIQLPIEQRKIGYVFQDARLFPHYTVRGNLNYGVTDADPEYFASVTRLLAL
EPLLVRYPRDLSGGEKQRVAIGRALLSKPDLLLMDEPLASLDMPRKKEVMPFLENLAQHF
RLPILYVSHSMQEILRLADHLVVLEQGKVLSAGPIEQVWSSKAMRPWQSFSEQSTLFSAT
VAKHHQTYGLTQVRLAEDVWLWVQQVEADVGSSVRMQVRANDVSIALDKPTASSIRNILP
ARIVAIEHQQPSKKSVSLKLELAPHCYLWAVVTEWAHAELALEVGMPVFAQIKGVSVAQR
DVILTN