Protein Info for CSW01_17765 in Vibrio cholerae E7946 ATCC 55056

Annotation: TIGR01666 family membrane protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 725 transmembrane" amino acids 20 to 39 (20 residues), see Phobius details amino acids 45 to 60 (16 residues), see Phobius details amino acids 71 to 88 (18 residues), see Phobius details amino acids 94 to 112 (19 residues), see Phobius details amino acids 117 to 135 (19 residues), see Phobius details amino acids 141 to 164 (24 residues), see Phobius details amino acids 392 to 413 (22 residues), see Phobius details amino acids 419 to 436 (18 residues), see Phobius details amino acids 443 to 462 (20 residues), see Phobius details amino acids 468 to 484 (17 residues), see Phobius details amino acids 491 to 513 (23 residues), see Phobius details amino acids 517 to 535 (19 residues), see Phobius details TIGR01666: TIGR01666 family membrane protein" amino acids 14 to 716 (703 residues), 1264.4 bits, see alignment E=0 TIGR01667: integral membrane protein, YccS/YhfK family" amino acids 14 to 715 (702 residues), 805.1 bits, see alignment E=4.9e-246 PF12805: FUSC-like" amino acids 72 to 352 (281 residues), 384.1 bits, see alignment E=7.1e-119 PF04632: FUSC" amino acids 395 to 709 (315 residues), 43 bits, see alignment E=5.3e-15 PF13515: FUSC_2" amino acids 407 to 528 (122 residues), 94 bits, see alignment E=1.6e-30 PF11744: ALMT" amino acids 412 to 588 (177 residues), 22 bits, see alignment E=1.5e-08

Best Hits

KEGG orthology group: None (inferred from 100% identity to vcm:VCM66_A0676)

Predicted SEED Role

"Putative efflux (PET) family inner membrane protein YccS"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (725 amino acids)

>CSW01_17765 TIGR01666 family membrane protein (Vibrio cholerae E7946 ATCC 55056)
MCCAVPKINQLRLYWANKTVNYSVLILLTLLGVVIPAWYYQLNTWITPLILGVIAAALAD
RDDRFSGRLKSIILTLICFAIAAFSIEILFQTPWLFALGLFTSSFGFIMLGAMGARYASI
AFASLLVAVYTMLGAHQSTNIWFQPLLLLSGSAWYYLMSMLWHAFWPMQPVQQNLANVFL
QLANYLEAKSTLFHPVSNMIPQPHRIIEANLNAATVNALNQCKAVFLTRSKRGHVDSASD
RFLNIYFLAQDIHERVSSSHYRYQELADHFGRSDILFRFKYLLETQAKACRDIAQSIRLG
HSYQHDSASIVALDELQLSLSYLRQQERRDWKSLLGQLGYLFNNLATVEKQLNNVSNPDV
AKPEEGVLDDTEAHTLGSMWQRIRANLNKDSLLFRHALRLSITLTLGYAIIQGFGIERGY
WILLTTLFVCQPNYAATKQKLTARIIGTLAGLLIGVPLLTFFPSQESQLVFIVFSGVMFF
AFRLNNYGYATGFITLLVLFCFNQLGEGYAVVLPRLADTLIGCALAVAAVVLILPDWQSK
RLHKVMAEAIDANKQYLAQIIGQYRIGKKDSLSYRIARRHAHNQDAALSAAVTNMLAEPG
RYRAAADESFRFLTLNHALLSYISALGAHRTRLDDETVHQLVLDSHRVIHQHLDLLHQQL
SNHCEECDTSGIDSSGLEKRLAEWREDDEGSARMVLQQLHLIYRMLPELHTLASKFAVKV
DSQSD