Protein Info for CSW01_17685 in Vibrio cholerae E7946 ATCC 55056
Annotation: chitinase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: K01183, chitinase [EC: 3.2.1.14] (inferred from 99% identity to vco:VC0395_0638)Predicted SEED Role
"Chitodextrinase precursor (EC 3.2.1.14)" in subsystem Chitin and N-acetylglucosamine utilization (EC 3.2.1.14)
MetaCyc Pathways
- chitin degradation II (Vibrio) (3/6 steps found)
- chitin degradation III (Serratia) (3/7 steps found)
- chitin degradation I (archaea) (2/7 steps found)
KEGG Metabolic Maps
Isozymes
Compare fitness of predicted isozymes for: 3.2.1.14
Use Curated BLAST to search for 3.2.1.14
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Compare to protein structures
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (1051 amino acids)
>CSW01_17685 chitinase (Vibrio cholerae E7946 ATCC 55056) MRVLEGKAGKSVFTLSTLTASCLMAFSSYAAVDCSTLPEWQSSAVYTGGAKVQHKGNAYQ ANYWTQNNDPETFSGNYAQWKLLDSCSTSGGTNQAPSVTLTAPLATAQVKAGEVMTLAAN ASDADGSVARVEFSVDGVLVGQATKAPYSASWTATKGTHEFSAVAFDDKGAVSTKNAVTL TVSDAGPANQAPTVAVALSASSVDVGTVVTLSAEAADADGSVEKVDFYVGGALVGTSAKA PYTLNYTATKAGSLAVYARATDNLGAATDSALTTLVVNGVAPVANCRPDGLYQTEGVQVP YCTVYDADGREKMGVDHPRRVIGYFTSWRSGDDPQAAYLVKDIPWEQLTHINYAFVSIGS DGKVNVGDVNDPNNAAVGKEWPGVEIDPTLGFKGHFGALATYKQKYGVKTLISIGGWAET GGHFDANGNRVADGGFYTMTTNADGSINHAAIEKFAASAVEMIRKYKFDGVDIDYEYPTS MAGAGNPDDKGFMEPRRAYLWASYQELMRVLREKLDQASAQDGHHYMLTIAAPSSGYLLR GMETFDVTKYLDYVNIMSYDLHGAWNDHVGHNAALYDTGKDSELAQWNVYGTAQYGGIGY LNTDWAYHYFRGSMPAGRINIGVPYYTRGWQGVTGGENGLWGRAALPNQNLCAPGTGEGE KNNCGHGATGIDNMWHDVNAAGDEMGAGSNPMWHAKNLEKGIWGSYAAAYKLDPTTTPLI GTYVRNYDSVAVAPWLWNAEKKVFLSTEDKQSIDVKADYVIDKEIGGIMFWELAGDYSCY NLDANGKRTSVDPSEQACATGKGEYHMGNTMTKAIYDKFKVATPYGNKVATGAIPAEAVN IAVKVGGFKVGDQNYPINPKITFTNNTGIDIPGGTEFQFDIPVSAPDNAKDQSGGGLKVI ASGHTRANNIGGLDGTMHRVAFSLPAWKSLPAGATYELDMVYYLPISGPANYTVKINNVE YAFSFEQPDLPVADLTAGGNTGGNTGGNTGGGTGGGSTGDVIQWVPGSTQVQNGTTVTYN GKCFVAQNNPGVWESPTQSNWFWKEVTCPQA