Protein Info for CSW01_17660 in Vibrio cholerae E7946 ATCC 55056

Annotation: protein translocase subunit SecD

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 612 transmembrane" amino acids 20 to 41 (22 residues), see Phobius details amino acids 448 to 468 (21 residues), see Phobius details amino acids 475 to 497 (23 residues), see Phobius details amino acids 503 to 522 (20 residues), see Phobius details amino acids 543 to 567 (25 residues), see Phobius details amino acids 574 to 598 (25 residues), see Phobius details PF13721: SecD-TM1" amino acids 14 to 109 (96 residues), 79.3 bits, see alignment E=8e-26 PF07549: Sec_GG" amino acids 127 to 149 (23 residues), 20.2 bits, see alignment (E = 1e-07) TIGR01129: protein-export membrane protein SecD" amino acids 134 to 598 (465 residues), 429 bits, see alignment E=2e-132 PF21760: SecD_1st" amino acids 237 to 294 (58 residues), 82.2 bits, see alignment 4.2e-27 PF22599: SecDF_P1_head" amino acids 310 to 428 (119 residues), 113.7 bits, see alignment E=1.3e-36 TIGR00916: protein-export membrane protein, SecD/SecF family" amino acids 348 to 590 (243 residues), 246.2 bits, see alignment E=3.3e-77 PF02355: SecD_SecF_C" amino acids 430 to 599 (170 residues), 65.3 bits, see alignment E=1.5e-21 PF03176: MMPL" amino acids 506 to 589 (84 residues), 24.7 bits, see alignment E=3.2e-09

Best Hits

KEGG orthology group: K03072, preprotein translocase subunit SecD (inferred from 100% identity to vcm:VCM66_A0651)

Predicted SEED Role

"Protein-export membrane protein SecD (TC 3.A.5.1.1)" (TC 3.A.5.1.1)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (612 amino acids)

>CSW01_17660 protein translocase subunit SecD (Vibrio cholerae E7946 ATCC 55056)
MKKKTQNQAAKRLINHYSAWKYVVLVTTIIILTLSAIPTWYGEQPSIQLQSKDATSVLRN
VPELTQLLNKQNIQADEITQQGDNTTLVFANETQQSQARNALDALVKEGDTITYSYVSVA
PKWLGNLGFSPIKLGLDLRGGVQFLLNVDVDKAFQEQRDSMMDAVKDSLRAERLRGVVVQ
AMGNDAFEVKTEQPQALSHVRKYLQENYRGWEIRQGSDQLQVQPSQQNKSEFQTATIQQN
LKIMRDRIEELGITEALVQRQGEHAIRIELPGVQDPSQAKNVIGATASLAFYEAKSPTDA
RSYDDLILEDGNGRPVILAKRPVLSGEHIVNARAGVDNMGMSEVNISLDHAGGKIMSDFS
GKHIGKPMATVYREYKTNARGETVRSEKVISVATIQSQLGSQFRITGAGSMEEAQQLALL
LRAGSLTAPVTIVEERTIGASLGEENIANGFAALALGMAMTLTFMALWYRRLGWVANVAL
LVNMACLLGLIALLPGAVLTLPGIAGLVLTVGMAVDTNVLIFERIRDKLSEGRNFAQAID
TGFDSAFSTILDANITTMITAVILYSIGNGPIQGFALTLGLGLLTSMFSGVFASRALINL
VWGRDTRRDVRV