Protein Info for CSW01_17570 in Vibrio cholerae E7946 ATCC 55056

Annotation: ferredoxin-type protein NapF

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 168 TIGR00402: ferredoxin-type protein NapF" amino acids 12 to 160 (149 residues), 146 bits, see alignment E=4.1e-47 PF00037: Fer4" amino acids 37 to 56 (20 residues), 22.5 bits, see alignment (E = 5e-08) amino acids 137 to 159 (23 residues), 34.1 bits, see alignment (E = 1e-11) PF12800: Fer4_4" amino acids 38 to 51 (14 residues), 15.7 bits, see alignment (E = 1.1e-05) amino acids 70 to 83 (14 residues), 10.7 bits, see alignment (E = 0.00042) amino acids 112 to 122 (11 residues), 10.2 bits, see alignment (E = 0.0006) amino acids 142 to 155 (14 residues), 17.4 bits, see alignment (E = 2.9e-06) PF13237: Fer4_10" amino acids 38 to 83 (46 residues), 24.9 bits, see alignment E=1e-08 amino acids 111 to 155 (45 residues), 27.6 bits, see alignment E=1.4e-09 PF13187: Fer4_9" amino acids 39 to 84 (46 residues), 30.2 bits, see alignment E=2.4e-10 amino acids 112 to 159 (48 residues), 30 bits, see alignment E=2.9e-10 PF12838: Fer4_7" amino acids 40 to 83 (44 residues), 35.6 bits, see alignment E=6.9e-12 amino acids 112 to 158 (47 residues), 38.8 bits, see alignment E=6.8e-13 PF12837: Fer4_6" amino acids 137 to 158 (22 residues), 24.9 bits, see alignment (E = 9.2e-09) PF12798: Fer4_3" amino acids 144 to 158 (15 residues), 20.2 bits, see alignment (E = 5.5e-07)

Best Hits

Swiss-Prot: 47% identical to NAPF_HAEIN: Ferredoxin-type protein NapF (napF) from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)

KEGG orthology group: K02572, ferredoxin-type protein NapF (inferred from 100% identity to vcm:VCM66_A0634)

Predicted SEED Role

"Ferredoxin-type protein NapF (periplasmic nitrate reductase)" in subsystem Nitrate and nitrite ammonification

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (168 amino acids)

>CSW01_17570 ferredoxin-type protein NapF (Vibrio cholerae E7946 ATCC 55056)
MEKNMVDLSKRRWFTPNRQPNQSQVRLPWLARPDAFTDECTRCGKCVTACETHIIEKGDG
GFPTVNFSIDECTFCYQCAQSCPEPLFVAQSEAPWQAKVHITHHCLAQQQVECRSCQDAC
PEEAIHFALQIGRTASPQVNSEQCSGCGACVSVCPSNAMTVHYTQHIA