Protein Info for CSW01_17555 in Vibrio cholerae E7946 ATCC 55056

Annotation: LacI family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 343 PF00356: LacI" amino acids 18 to 61 (44 residues), 59 bits, see alignment 6.4e-20 PF00532: Peripla_BP_1" amino acids 74 to 337 (264 residues), 75.3 bits, see alignment E=1.2e-24 PF13407: Peripla_BP_4" amino acids 115 to 318 (204 residues), 48.6 bits, see alignment E=1.6e-16 PF13377: Peripla_BP_3" amino acids 181 to 340 (160 residues), 85.2 bits, see alignment E=1.1e-27

Best Hits

KEGG orthology group: None (inferred from 100% identity to vcm:VCM66_A0631)

Predicted SEED Role

"Transcriptional regulator, LacI family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (343 amino acids)

>CSW01_17555 LacI family transcriptional regulator (Vibrio cholerae E7946 ATCC 55056)
MTDKSRVMHSEKATVTSKDVAKLAGVSQSTVSRVFVPGSSVSEKTKQKVFEAAKVLNYRP
NAFARSLTTNESKLIGLVFPDADYPIHMKTLQLISSELQQVGYSAVLIPWQVDEQDNHSI
PNIFQYRVDGVIAASATFNKTLYEECEEFNIPIVQYARVVEGTKSSYVISDNYEAGRQAA
QLLHQAGAQSAVYLTGEVPTFTNDERQQGFCSEFKSLTGFTPPVVKATYDYTGSLDTIRR
LIADSSRPAAIFCATDNLAMAVMDIARFEFSLRIPDDIQVIGFDNIPQTEWLSYQLTTFA
QDFKRLARESVKIIVDQITTRNQSLVKLMVPTKLIQRKSTLKS