Protein Info for CSW01_17225 in Vibrio cholerae E7946 ATCC 55056

Annotation: putative 2-aminoethylphosphonate ABC transporter permease subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 592 transmembrane" amino acids 47 to 72 (26 residues), see Phobius details amino acids 83 to 100 (18 residues), see Phobius details amino acids 106 to 126 (21 residues), see Phobius details amino acids 138 to 161 (24 residues), see Phobius details amino acids 176 to 202 (27 residues), see Phobius details amino acids 224 to 248 (25 residues), see Phobius details amino acids 278 to 298 (21 residues), see Phobius details amino acids 329 to 353 (25 residues), see Phobius details amino acids 382 to 404 (23 residues), see Phobius details amino acids 421 to 441 (21 residues), see Phobius details amino acids 451 to 469 (19 residues), see Phobius details amino acids 507 to 534 (28 residues), see Phobius details amino acids 556 to 583 (28 residues), see Phobius details TIGR03262: putative 2-aminoethylphosphonate ABC transporter, permease protein" amino acids 50 to 592 (543 residues), 802.7 bits, see alignment E=8.5e-246 PF00528: BPD_transp_1" amino acids 135 to 305 (171 residues), 38.1 bits, see alignment E=7e-14 amino acids 410 to 579 (170 residues), 40.7 bits, see alignment E=1.1e-14

Best Hits

KEGG orthology group: K02011, iron(III) transport system permease protein (inferred from 100% identity to vch:VCA0601)

Predicted SEED Role

"Ferric iron ABC transporter, permease protein" in subsystem Campylobacter Iron Metabolism or Iron acquisition in Vibrio or Transport of Iron

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (592 amino acids)

>CSW01_17225 putative 2-aminoethylphosphonate ABC transporter permease subunit (Vibrio cholerae E7946 ATCC 55056)
MRTVVRSCRQRQQLQPAVLMRLKEKSMLNVARTFSVRILPHWSRDSLILSTTLLILLSLM
LLFIVAPLAAMLLKSVQNGQGEFVGLAYFAQYFSSAALWQSLRNTLVLGISVTAIVGILA
FGYAYALTRSCMPGKHLFRVLGSAPILAPSLLPAISLIFLFGNQGMLKSWLGGESIYGGL
GITLGLIFWTFPHALMILTTSLSTSDARLYEAARALKTSPIKTFFIVTLPAAKYGLISAL
IVVFTLVVCDFGVPKVIGGSYNVLATDIFKQVVGQQNFAMGAVTSIVLLLPAVFAFIADR
WVQKKQQSLFDTRSVAYQPAPHRLRDGLCLLYCVLICVAIVAVLATAVYGSLVTFWPWNT
ALTLKHYQFAETSAYGWSPYFNSLTLASLTALCGTVIIFLGAYSIEKGRVFALLRQAMQM
LSMVPMAVPGLVLGLGYIFFFNHASNPLNGLYGGMLLLVINTVVHYYTVGHMTAVTALKQ
LPPELEATAASIKLPQYRLLWKVTLPVSLPAVLDIASYLFINALTTTSAVVFLYSTDTVP
ASVAVLNMDDAGQTGAAAAMAVMIMLSAALAKLLHVGLEFGLFGRLQAWRKR