Protein Info for CSW01_17215 in Vibrio cholerae E7946 ATCC 55056

Annotation: multidrug transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 301 signal peptide" amino acids 1 to 18 (18 residues), see Phobius details amino acids 23 to 23 (1 residues), see Phobius details transmembrane" amino acids 19 to 22 (4 residues), see Phobius details amino acids 33 to 53 (21 residues), see Phobius details amino acids 65 to 87 (23 residues), see Phobius details amino acids 94 to 116 (23 residues), see Phobius details amino acids 121 to 138 (18 residues), see Phobius details amino acids 150 to 170 (21 residues), see Phobius details amino acids 190 to 213 (24 residues), see Phobius details amino acids 226 to 248 (23 residues), see Phobius details amino acids 254 to 276 (23 residues), see Phobius details amino acids 281 to 300 (20 residues), see Phobius details TIGR03340: phosphonate utilization associated putative membrane protein" amino acids 4 to 297 (294 residues), 409.3 bits, see alignment E=4.9e-127 PF00892: EamA" amino acids 5 to 136 (132 residues), 34.3 bits, see alignment E=1.4e-12

Best Hits

KEGG orthology group: None (inferred from 100% identity to vcj:VCD_000720)

Predicted SEED Role

"Permease of the drug/metabolite transporter (DMT) superfamily" in subsystem Queuosine-Archaeosine Biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (301 amino acids)

>CSW01_17215 multidrug transporter (Vibrio cholerae E7946 ATCC 55056)
MSFMPIILVLFSALLHAGWNIIGKRYQSSGPSFFLGATSATSLLLTPYIVWYFTKIGWST
LPTQFWLLLVVSGLSQMVYMLGLAFAYSKVDIGIAYPLARGLPVLLVGAGTVMLGYDLQL
NQWLGFALITLGCLMIPLQKFRQFRFADYANLGIVWALVAALGTAGYSIIDKEALAIIEQ
TVGSQMPASYSAVLYLGIQFWAMCIPLAIWYLLTGQRAPFVEAWRIRYTATLAGLMMGGT
YSLVLYAMTLTENVSFIVALRQTSIVFGLFMGIAFLGERWYVTRLLGVSAIVAGLVVAFA
R