Protein Info for CSW01_17115 in Vibrio cholerae E7946 ATCC 55056

Annotation: SgrR family transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 565 PF12793: SgrR_N" amino acids 5 to 119 (115 residues), 144.6 bits, see alignment E=1.5e-46 PF00496: SBP_bac_5" amino acids 164 to 306 (143 residues), 73.3 bits, see alignment E=2.1e-24

Best Hits

KEGG orthology group: K11925, SgrR family transcriptional regulator (inferred from 100% identity to vcj:VCD_000741)

Predicted SEED Role

"SgrR, sugar-phosphate stress, transcriptional activator of SgrS small RNA" in subsystem Sugar-phosphate stress regulation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (565 amino acids)

>CSW01_17115 SgrR family transcriptional regulator (Vibrio cholerae E7946 ATCC 55056)
MSSPRLRVQFETLFEHFQGQDVETQLEDVTDILFCTRRNARIVLNKMEEEGWIEWHPAAG
RGKLSQLIFKRSRADVSENLARRYLNEGKIGQAFAVLDQDAAKLTQVIESYLGVQHQEGL
QVVRLPYYRQLSMLNPQKPMRRSEQHIARQVFSGLTRLDEEEQLQPDLAHAWQALSDTHW
RFYLRPGVRFHNGNLLTTELIVQNLWQLRLLNLFAHIDRVDSPYPWAVDVHLQKPDTRLP
LLLAEACAKILPAESDRNPDFDLMPVGTGPYKVVLNDEKRLVLQAFDGYFGFRPLLDRVE
VWVIDEVHSSMVFPSLSNPMKTARGSSTEEVELDPGCTYLLLNRRNGVAKDEHWARYLTD
KLNALNLFRLLPEEKIIELGVLPAYGLKPGWYHHSAAAQRTLPPESKELTIAYHAQHPMF
PTVANAIKQLLSQDGITVNVIKYEHTVVETENVDIWIKPMGIANHRDDALAGWLLNYSDI
EFLSKGEDFNQWVSLIDAWRADSSALFPAKELGKSLVEKHQLIPMFHCWLGISKDQCGAL
QNAKCNALGWFDFSQVWVKPDLSEH