Protein Info for CSW01_17045 in Vibrio cholerae E7946 ATCC 55056

Annotation: NAD(P)(+) transhydrogenase (Re/Si-specific) subunit beta

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 458 transmembrane" amino acids 6 to 24 (19 residues), see Phobius details amino acids 33 to 51 (19 residues), see Phobius details amino acids 57 to 75 (19 residues), see Phobius details amino acids 87 to 107 (21 residues), see Phobius details amino acids 119 to 143 (25 residues), see Phobius details amino acids 163 to 179 (17 residues), see Phobius details amino acids 185 to 204 (20 residues), see Phobius details amino acids 213 to 232 (20 residues), see Phobius details amino acids 237 to 257 (21 residues), see Phobius details PF02233: PNTB" amino acids 7 to 456 (450 residues), 668.8 bits, see alignment E=2.3e-205

Best Hits

KEGG orthology group: K00325, NAD(P) transhydrogenase subunit beta [EC: 1.6.1.2] (inferred from 100% identity to vco:VC0395_0498)

Predicted SEED Role

"NAD(P) transhydrogenase subunit beta (EC 1.6.1.2)" in subsystem Phosphate metabolism (EC 1.6.1.2)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.6.1.2

Use Curated BLAST to search for 1.6.1.2

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (458 amino acids)

>CSW01_17045 NAD(P)(+) transhydrogenase (Re/Si-specific) subunit beta (Vibrio cholerae E7946 ATCC 55056)
MSAGLVQAAYIVAAVFFIMSLAGLSKQESARMGNYYGIAGMAMALLATIFSPNAEGLAWV
LLAMVIGGGIGIHYAKKVEMTEMPELVAILHSFVGMAAVLVGFNSYIDAPEAATHAEHVI
HLVEVFLGIFIGAVTFTGSIVAFGKLRGIIKSTPLNLPHKHKLNLAALVVSGLLLIHFVN
VDGSVFALIVMTLIAFAFGYHLVASIGGADMPVVVSMLNSYSGWAAAAAGFMLANDLLIV
TGALVGSSGAILSYIMCKAMNRSFISVIAGGFGQEVVISSDEEQGEHRETSAEEVAEMLK
NSKSVIITPGYGMAVAQAQYPVYEITEKLRAQGVTVRFGIHPVAGRLPGHMNVLLAEAKV
PYDIVLEMDEINDDFSDTDTVLVIGANDTVNPAALEDPNSPIAGMPVLEVWDAKNVIVFK
RSMNTGYAGVQNPLFFKENTMMLFGDAKESVDSIAKAL