Protein Info for CSW01_16935 in Vibrio cholerae E7946 ATCC 55056

Annotation: formate transporter FocA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 483 transmembrane" amino acids 35 to 56 (22 residues), see Phobius details amino acids 75 to 99 (25 residues), see Phobius details amino acids 119 to 141 (23 residues), see Phobius details amino acids 164 to 185 (22 residues), see Phobius details amino acids 197 to 225 (29 residues), see Phobius details amino acids 254 to 277 (24 residues), see Phobius details TIGR04060: formate transporter FocA" amino acids 16 to 281 (266 residues), 370.3 bits, see alignment E=4.8e-115 PF01226: Form_Nir_trans" amino acids 16 to 277 (262 residues), 246.3 bits, see alignment E=3e-77 TIGR00790: formate/nitrite transporter" amino acids 29 to 281 (253 residues), 256.2 bits, see alignment E=3e-80 PF00571: CBS" amino acids 313 to 364 (52 residues), 43.8 bits, see alignment 2.6e-15

Best Hits

KEGG orthology group: None (inferred from 100% identity to vcj:VCD_000787)

Predicted SEED Role

"Formate efflux transporter (TC 2.A.44 family)" in subsystem Fermentations: Mixed acid

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (483 amino acids)

>CSW01_16935 formate transporter FocA (Vibrio cholerae E7946 ATCC 55056)
MSAAYSKNQNCFSPTEMMAEAEKFALSKAKKTSGMILGLSVMAGAFIGLAFLFYITVTTG
SASAGWGLSRLAGGVAFSMGLILIVICGGELFTSSVLSSISWANREISFGKMLSIWGKVY
VGNFIGAIFLLLLVTAAGLYQLDEGQWGLNALNIAQHKLHHTTVQAFALGILCNLLVCLA
IWLTFSSANAMTKAAMTIMPVAMFVSSGFEHCVANMFMVPLGIVIQNFAPDSFWQQVGVT
ASQYSDLNVTQFITANLIPVTLGNIVGGAVLVGLANWSIYRRPQLKAANVVTITETQALT
SVKETLMKSTITVKDMMNSQPVTLSVDMTTPAAIDTLLDHHLSAAPVVDMQGRLVGVLSS
HDVMVDLWCQDYLPSQDQKVVDLMTRDVIAIDVNDKLVDVAEFFCIDKEQLFPTTSMGIA
TRFSALSLEERAKSMKVNKPHMLPVLHNGQLVGVLERNDVLEALRPIYGERVRIVKDKAL
ARA