Protein Info for CSW01_16885 in Vibrio cholerae E7946 ATCC 55056

Annotation: pyruvate:ferredoxin (flavodoxin) oxidoreductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1079 TIGR02176: pyruvate:ferredoxin (flavodoxin) oxidoreductase" amino acids 4 to 890 (887 residues), 980.8 bits, see alignment E=5.2e-299 PF01855: POR_N" amino acids 14 to 244 (231 residues), 248.2 bits, see alignment E=6.5e-77 PF17147: PFOR_II" amino acids 266 to 372 (107 residues), 58.8 bits, see alignment E=4.1e-19 PF01558: POR" amino acids 424 to 606 (183 residues), 96.9 bits, see alignment E=1.1e-30 PF10371: EKR" amino acids 635 to 670 (36 residues), 44.3 bits, see alignment (E = 8.7e-15) PF00037: Fer4" amino acids 674 to 697 (24 residues), 28.4 bits, see alignment (E = 7.5e-10) PF12837: Fer4_6" amino acids 674 to 696 (23 residues), 28.4 bits, see alignment (E = 7.9e-10) PF13183: Fer4_8" amino acids 679 to 748 (70 residues), 33.5 bits, see alignment 3.5e-11 PF13187: Fer4_9" amino acids 681 to 748 (68 residues), 29.1 bits, see alignment 5.7e-10 PF13484: Fer4_16" amino acids 681 to 747 (67 residues), 34.8 bits, see alignment 1.6e-11 PF12838: Fer4_7" amino acids 681 to 747 (67 residues), 41.9 bits, see alignment 8.1e-14 PF13534: Fer4_17" amino acids 681 to 747 (67 residues), 23.9 bits, see alignment 3.5e-08 PF02775: TPP_enzyme_C" amino acids 929 to 1041 (113 residues), 37.8 bits, see alignment E=1.1e-12

Best Hits

KEGG orthology group: K03737, putative pyruvate-flavodoxin oxidoreductase [EC: 1.2.7.-] (inferred from 100% identity to vcm:VCM66_A0489)

Predicted SEED Role

"Pyruvate-flavodoxin oxidoreductase (EC 1.2.7.-)" in subsystem Methionine Degradation or Pyruvate:ferredoxin oxidoreductase (EC 1.2.7.-)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.2.7.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1079 amino acids)

>CSW01_16885 pyruvate:ferredoxin (flavodoxin) oxidoreductase (Vibrio cholerae E7946 ATCC 55056)
MTWITDANTAVARVAYQLSEVLAVYPITPSTSMAESCEQWASQQKSNLLGDVPKLVEMQS
EAGSIAVVHGAAMSGALATTFTSSQGLLLMIPSLYKLAGELTPCVIHVAARTVATHALSI
YCDHSDVMAIRQTGVAMLCASNAQEAQDLAAIATFSALQCRLPFVHFFDGFLTSHAITQI
EPLSEEALSALLPMPALVDFRTRVLTPDRPTLRGATADPDSYFQCREAQTPYHQSTPEQV
QNIMDCFETQTGRRYQLAEYIGHPQAQSVIVAMGSSVDTIKQVVLAGVQQGERIGVIQIR
LYRPFPSQALRDALPATVTHISVLDRTKEPGSHGEPLYLDVLSALYTQRANSIRLSRGRY
GLSGKAFYPEDVEAIFTMMQAPEQEQMHEFVVGIEDDVSQLTLPKTISATRDKPYQSVLM
YGYGGDGSVSAGKNLIKTLGQNWHVQGQFEYDSKKSANVTTTHIRFSQQPITAPYPVRHA
WLVSLSNLKLLHERDIASKLIANGYLLLNTALTGQALWAALPPALQSRLQALSVQVATID
ADGLLERHQLGNKTSIVMQAAAARLLSQHTEQALLTPLEASLTEQLKHRSAQQLTQSLQC
LNQAYQSVCEMPFAIPSETTMAIQSQPKIWGASLVEQLLAGKGDALPVSAYPADGVWPTN
TSQLEKRNLAEQLPVWETDLCTQCGYCVAICPHSAIRARIVSETHPTLSELKSLPYRSRQ
QPDAHYVLQVSPDDCTGCQLCTQVCPAKDRQEPERKALNMVEKNLSYQSEQQRFTHFQAL
PKQSAYQQQRIDVKTLQHVEPYFEYPNACAGCGETPYIRILTQLFGDRLMIANATGCSSI
FGGNLPSTPYSQDSDGRGPAWANSLFEDNAEFGLGMNMALEALQSRAQRLLGGHTPQSPL
PDLRSQIGELKQRLPAHSEEQLLADYLSEKMVWMIGGDGWAYDIGFGGLDHVMRSGRNIN
ILVLDTQCYSNTGGQKSKSTPQGQTAKLCSLPNPSPAKDLVKLYQDLPGAFVARIALGAN
INQTIKALQAAGEHSGPSLVVAYSPCIEHHYDLAHSAQVTKEVVKSGAWPLYAGVAQQD