Protein Info for CSW01_16820 in Vibrio cholerae E7946 ATCC 55056

Annotation: PTS fructose transporter subunit IIBC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 580 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details transmembrane" amino acids 254 to 274 (21 residues), see Phobius details amino acids 285 to 309 (25 residues), see Phobius details amino acids 321 to 346 (26 residues), see Phobius details amino acids 367 to 387 (21 residues), see Phobius details amino acids 406 to 425 (20 residues), see Phobius details amino acids 445 to 468 (24 residues), see Phobius details amino acids 481 to 500 (20 residues), see Phobius details amino acids 507 to 528 (22 residues), see Phobius details amino acids 547 to 568 (22 residues), see Phobius details PF02302: PTS_IIB" amino acids 7 to 88 (82 residues), 56.9 bits, see alignment E=2.7e-19 amino acids 128 to 209 (82 residues), 65.8 bits, see alignment E=4.4e-22 TIGR00829: PTS system, Fru family, IIB component" amino acids 127 to 210 (84 residues), 123.1 bits, see alignment E=4.6e-40 TIGR01427: PTS system, Fru family, IIC component" amino acids 231 to 570 (340 residues), 473.1 bits, see alignment E=6.2e-146 PF02378: PTS_EIIC" amino acids 250 to 514 (265 residues), 74.3 bits, see alignment E=9.9e-25

Best Hits

KEGG orthology group: K02769, PTS system, fructose-specific IIB component [EC: 2.7.1.69] K02770, PTS system, fructose-specific IIC component (inferred from 100% identity to vcm:VCM66_A0475)

Predicted SEED Role

No annotation

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.1.69

Use Curated BLAST to search for 2.7.1.69

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (580 amino acids)

>CSW01_16820 PTS fructose transporter subunit IIBC (Vibrio cholerae E7946 ATCC 55056)
MKMKIAIVTACPSGVANSIIAAGLLQQASKTLGWEAYIECHSTVIAGHTLSEEEINKADL
VILAANGKIDMQRFVGKKVYQSPITACTSDPVGYLKQAAEQATELSSEQATRCDSPATAS
VSAKKIVAITACPTGVAHTFMAAEALEAEATRQGHQIKVETRGSVGAKNQLTEQEIAAAD
LVIIAADIDVPLDRFNGKKLYKTSTGLTLKKTAQELSNAFAQAKTFSSSANSATNEKAEE
KKGVYKHLMTGVSHMLPVVVAGGLIIALSFVFGIEAFKEEGTLAAALMQIGGGSAFALMI
PVLAGYIAFSIADRPGLAPGLIGGMLASSTGAGFLGGIVAGFLAGYSAKFIADKVQLPQS
MAALKPILIIPFIASLFTGLVMIYVVGGPMSSIMSGMTSFLNNMGSTNAILLGIVLGAMM
CFDLGGPVNKAAYTFGVGLLASQTYAPMAAIMAAGMVPALGMGLATFIAKDKFEAGEREA
GKASFVLGLCFISEGAIPFAAKDPMRVIPACMVGGAVTGALSMLFGAKLMAPHGGLFVLL
IPNAISPVLLYLVAIAVGTAITGFGYAMLKKSAQAKAVAA