Protein Info for CSW01_15160 in Vibrio cholerae E7946 ATCC 55056

Annotation: sensor histidine kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 549 signal peptide" amino acids 1 to 38 (38 residues), see Phobius details transmembrane" amino acids 206 to 226 (21 residues), see Phobius details PF00672: HAMP" amino acids 224 to 276 (53 residues), 53.8 bits, see alignment 3e-18 PF00512: HisKA" amino acids 313 to 378 (66 residues), 46.4 bits, see alignment E=5e-16 PF02518: HATPase_c" amino acids 430 to 539 (110 residues), 73.7 bits, see alignment E=2.5e-24

Best Hits

KEGG orthology group: None (inferred from 100% identity to vch:VCA0238)

Predicted SEED Role

"Sensor protein torS (EC 2.7.3.-)" in subsystem trimethylamine N-oxide (TMAO) reductase (EC 2.7.3.-)

Isozymes

Compare fitness of predicted isozymes for: 2.7.3.-

Use Curated BLAST to search for 2.7.3.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (549 amino acids)

>CSW01_15160 sensor histidine kinase (Vibrio cholerae E7946 ATCC 55056)
MRLIERRQFWEMTMFRYRLAFVLALLLTLILAQVGVAYWSNQVANQHLLRGQISSQILQG
FMQLSTEKQQLKVWLAEYLLIKDGSTLKRDMRFSKIEALLHKLNLLTEQAQQHSLTVQDF
SEINQQIKVISLFETNFASLKKALRSWEIAKITDDDERWLLLSQSFDRVDDTDLRQLLTQ
AISLQQQRTSRYEEAALDALSNVRSVITSLAVFGMVSGALLGVWLLRTLSKPLAELVKST
TALEQGRLDHRISISGPDELKTLARHFNYMAQSLEQAQQKERMSRQLIEREVADRTQELA
QALQTLEKAKHQQKEFFANVSHELRSPATAILGEAQITLRSRHNSDDEYRQTLLRISESA
EQLAFRIEDLLMLIRHDERLFHPALTELLLGEIWQAVVRQASLLTHAQQVELTVNTPAQG
EWQTQLCYTDCDKLLMVIRILVDNALRYDPTQQPIGLNLELDEEAWRVQLVDQGIGIAEA
DLSVIFERYFRAENGKRYRPDGLGIGLTLAQSIVKQLDGEIRIESVLEQGTTVTLTFPRG
EEQDANLID