Protein Info for CSW01_14900 in Vibrio cholerae E7946 ATCC 55056

Annotation: regulatory protein LuxO

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 530 signal peptide" amino acids 1 to 20 (20 residues), see Phobius details PF01590: GAF" amino acids 23 to 156 (134 residues), 36.3 bits, see alignment E=2.3e-12 PF00158: Sigma54_activat" amino acids 194 to 360 (167 residues), 233.7 bits, see alignment E=3e-73 PF14532: Sigma54_activ_2" amino acids 195 to 365 (171 residues), 80.1 bits, see alignment E=5.8e-26 PF07728: AAA_5" amino acids 217 to 338 (122 residues), 31.7 bits, see alignment E=4.3e-11 PF00004: AAA" amino acids 218 to 347 (130 residues), 22.1 bits, see alignment E=5.5e-08

Best Hits

Swiss-Prot: 100% identical to LUXO_VIBC3: Regulatory protein LuxO (luxO) from Vibrio cholerae serotype O1 (strain ATCC 39541 / Classical Ogawa 395 / O395)

KEGG orthology group: K12266, anaerobic nitric oxide reductase transcription regulator (inferred from 100% identity to vco:VC0395_1095)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (530 amino acids)

>CSW01_14900 regulatory protein LuxO (Vibrio cholerae E7946 ATCC 55056)
MQEFSLSTLLEMTVGLASGANNEERFHRLLDAVRKAVICDCVVLMSLHNDTLTPLAMQGL
TRDTLGRRFVVSEHPRLAQICSADLPVRFAADCPLPDPFDGLLLDSEDDLPMHSCMGLPL
HFGEQLLGILTLDSLKPDAFDHLSPRSLEILAAIAAATLKMTLTFSELENQAKQTQLRLE
ELNQEAWSRDSVEIIGNSGPMLAMKADIDVVAPSQFNILIHGETGVGKELVARTIHQRSN
RKRQPLVYVNCAAIPENLLESELFGHVKGAFTGADRARMGKFALADGGTLFLDEIGELPL
SAQSKILRALQNHEIQPVGQDRVQTVDVRILAATNRDLKKEVEAGRFRADLYHRLSVYPI
YVPPLRERKGDLSLLAGYFVEQARRKLGITQLKLHGDVLSQLIQYPWPGNVRELEHVINR
AALKAKARQRGRPVTTLKVEDLGELQGPRAAMVEPTAQDEPMLGEWIGELGLRDATDEFQ
RHLISETLTQADFNWAEAARRLQTDRANLTRLAKRLGITVSRSHSIERSR