Protein Info for CSW01_14825 in Vibrio cholerae E7946 ATCC 55056

Annotation: GGDEF domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 710 TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 529 to 695 (167 residues), 124.3 bits, see alignment E=2e-40 PF00990: GGDEF" amino acids 532 to 694 (163 residues), 128.9 bits, see alignment E=1.6e-41

Best Hits

KEGG orthology group: None (inferred from 100% identity to vco:VC0395_1112)

Predicted SEED Role

"GGDEF family protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (710 amino acids)

>CSW01_14825 GGDEF domain-containing protein (Vibrio cholerae E7946 ATCC 55056)
MFPRTLLKRVTSSRNYRMLAETTFEYLTTFLLSQSAGIVRAPSQDVAGHTLLSSNTFTPL
EAYPEAFWAWAAQFDTSDGLIPFAINTCRWNYLPVMGGESFIFMLDNHPQHRTYLIIQAA
CVDKVHLSTQSGELDFLQLIAAKWQCLRAEIEASKEFKNRDLREAQYLSEIRQREQFIDN
MKLVHQVALELSNPANLDELHRASVEAMRHRLGFDRSALLLLDMKKRCFSGTYGTDEHGN
TIDEQHTQYDLHQLEPQYLEALSNEECTLMVVEDVPLYTVGQVVGQGWNAMLILRDGNDT
IGWIAIDNYINRQPITEYQKQMLESFGSLLAQIYIRKKQEQNVRMLHASMVELSRCMTVS
EVCKSAVTFAINRMGIDRMAVFLTDEACSYIQGTWGTDIQGNIVDESYFRGSTHENDIVD
LAKVYPNEVVFKESVPIYHDCKIVGYGWTAMTMLTDKGTPIAFIAADNLIRRSPLTSQLR
EVIRMFASNLTEVLMRAKAQEAISVLNETLELEVRNRTRDLQKANEKLDLMAKLDPLTRL
GNRRMLEHQLEQTCEQTIKEVVNYGVILLDIDHFGLFNNCYGHLEGDIALMRIGNILSRH
AQSEHELFCRIGGEEFLLLVANRSAEEIHLLAENIRKSIEAECIEHCENPSGELLTVSIG
YAASRYKPREIQFDQLYAEADKALYRAKSQGRNQVIGVIVENIDCIQAEM