Protein Info for CSW01_14785 in Vibrio cholerae E7946 ATCC 55056

Annotation: proton-conducting membrane transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 891 transmembrane" amino acids 20 to 38 (19 residues), see Phobius details amino acids 64 to 85 (22 residues), see Phobius details amino acids 96 to 128 (33 residues), see Phobius details amino acids 148 to 172 (25 residues), see Phobius details amino acids 192 to 215 (24 residues), see Phobius details amino acids 227 to 244 (18 residues), see Phobius details amino acids 256 to 277 (22 residues), see Phobius details amino acids 284 to 303 (20 residues), see Phobius details amino acids 307 to 330 (24 residues), see Phobius details amino acids 351 to 370 (20 residues), see Phobius details amino acids 390 to 413 (24 residues), see Phobius details amino acids 438 to 459 (22 residues), see Phobius details amino acids 491 to 515 (25 residues), see Phobius details amino acids 554 to 573 (20 residues), see Phobius details amino acids 585 to 605 (21 residues), see Phobius details amino acids 611 to 632 (22 residues), see Phobius details amino acids 638 to 655 (18 residues), see Phobius details amino acids 673 to 694 (22 residues), see Phobius details amino acids 731 to 750 (20 residues), see Phobius details amino acids 762 to 783 (22 residues), see Phobius details amino acids 790 to 810 (21 residues), see Phobius details amino acids 825 to 850 (26 residues), see Phobius details amino acids 865 to 884 (20 residues), see Phobius details PF00662: Proton_antipo_N" amino acids 50 to 94 (45 residues), 45.7 bits, see alignment 1.2e-15 PF00361: Proton_antipo_M" amino acids 113 to 396 (284 residues), 189.4 bits, see alignment E=2.1e-59 PF13244: MbhD" amino acids 595 to 658 (64 residues), 49.8 bits, see alignment 7.9e-17 PF20501: MbhE" amino acids 670 to 750 (81 residues), 73.4 bits, see alignment E=3.2e-24 PF04039: MnhB" amino acids 763 to 880 (118 residues), 92.8 bits, see alignment E=5.1e-30

Best Hits

KEGG orthology group: K05565, multicomponent Na+:H+ antiporter subunit A (inferred from 100% identity to vch:VCA0157)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (891 amino acids)

>CSW01_14785 proton-conducting membrane transporter (Vibrio cholerae E7946 ATCC 55056)
MKTGLDKHTSLIPNTVSARLLPFAVLPILLFGWVFYWHQTGGNAWQVTWVPGLDLNLSFR
LDGLSFLFASLITGIGALIQIYALAYMKEKAARFSFHLYLTLFMLAMLGVVVSDNILLLF
IFWELTTITSYLLIGFNHDKPVSRKNALQSLLVTGAGGLALLAGLILLGLMANSYQISVI
IEHADHIAQHPWFMPSLILVLLGAFTKSAQFPFHFWLPNAMAAPTPVSAYLHSATMVKAG
IYLLARLSPIYASSDFWFYCLTIVGAVTALWCALLAFKQTDLKLMLAYSTNVALGKLTLL
LGLGTEVALTAAVLFIFAHSFYKAALFMVVGNIDKATGTREREKLGNLKSVLLLSLIAAV
IAALSKSGVAPMLGFLSKEYMYKSSVESGIAWISLVLLLINALMVALAIALLYKPFFGQA
TKESESHPPKAIEQKKSLWLPAMGLAIASFLLPVFALDWINQHLVIPAVMAMDPNSVPQA
AKLWQGFNIPLALSGITLVLGGVLYLNYATLVTWLTRLVKPLPKAEQMFDAVLAYLATLA
SWQTQMLQQKRSSGYMLLFFAVLALILIYQPLPLPATFSASLFDVHFYEVAIALALIASA
LLCVLSTSRLLSVLALGMAGFMTTLVFMIYSAPDVAKTLLLVETLMVVFVVLLMRHVPYL
STVARHSVPRRTLNAVIASVIGASVTLILLNITAHPIDTTLSDYFAQQSVPGGHGRNIVN
VILVDFRAFDTLGEVIVVVMASLVAISLLPKRTEQPQKIHSLIFATTAHIVTALMLMFSL
YLLLRGHNAPGGGFIGALIAVIGFSLLLFAESPQYVRDRLHFSPLNIALFGILLSFMAGA
MSVAVGLPFLTGLWWKEILPLGTPLLFDVGIYLAIIGGVMSMLLRVKEELD