Protein Info for CSW01_14735 in Vibrio cholerae E7946 ATCC 55056

Annotation: C4-dicarboxylate ABC transporter permease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 713 transmembrane" amino acids 20 to 41 (22 residues), see Phobius details amino acids 50 to 69 (20 residues), see Phobius details amino acids 80 to 100 (21 residues), see Phobius details amino acids 112 to 130 (19 residues), see Phobius details amino acids 137 to 160 (24 residues), see Phobius details amino acids 182 to 205 (24 residues), see Phobius details amino acids 224 to 243 (20 residues), see Phobius details amino acids 305 to 327 (23 residues), see Phobius details amino acids 348 to 368 (21 residues), see Phobius details amino acids 374 to 390 (17 residues), see Phobius details amino acids 411 to 433 (23 residues), see Phobius details amino acids 450 to 476 (27 residues), see Phobius details amino acids 550 to 569 (20 residues), see Phobius details amino acids 575 to 592 (18 residues), see Phobius details amino acids 604 to 621 (18 residues), see Phobius details amino acids 626 to 646 (21 residues), see Phobius details amino acids 654 to 671 (18 residues), see Phobius details amino acids 677 to 694 (18 residues), see Phobius details TIGR02123: TRAP transporter, 4TM/12TM fusion protein" amino acids 24 to 699 (676 residues), 765.8 bits, see alignment E=1.9e-234 PF06808: DctM" amino acids 122 to 617 (496 residues), 233 bits, see alignment E=3.1e-73

Best Hits

KEGG orthology group: None (inferred from 100% identity to vch:VCA0146)

Predicted SEED Role

"TRAP-type uncharacterized transport system, fused permease component"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (713 amino acids)

>CSW01_14735 C4-dicarboxylate ABC transporter permease (Vibrio cholerae E7946 ATCC 55056)
MSNSVEQELEKFEVPTRTRFGWVTRTISVLCVLLSLAHIWFNTLSTWSELWISAIHFAGF
AMICALWYPALPRWRGSKVALAFDVLLALLALACLIYLMLAEDALYERGVKFVTSDWVFS
ILAILIVMEMIRRTMGWFIPTLILICLTYVSVWGKWAGGIFHFPGLSAETLLYRSFYSSE
GMFGSIAAISWSFVFMFILFGAFLVRSGVGDYIMDVSRAAAGKVVGGPGFIAVLASGLMG
SVSGSSVANTVSTGVITIPMMKKAGFPARFAAGVEAAASTGGQLMPPVMGAGAFIMASYT
QIPYVDIVAVSFIPALIYFLSVAFFVRIEAKRMGVQIVTTSQEPFMKVLLSGWHNLIPLA
VLVTLLVVGFTPTYAAGLSILSVIVASWFSKNHKMGPKAIIEALEQGAKNMATTAVLLVG
IGLVINVISTTGIGNTFSLMINNWANGDLLTMLVLITLASLVLGMGLPVTAAYIVLGTLS
APALYKLLAESQLVDLMVSGQLPEQAKAIFMLAAPDQLSLLNAPMAAEKAHELISLVPAD
FVETLLQQSLGLEAIGLALLSAHLIIFWLSQDSNVTPPVCLTAFAAATIAKTPPMRTGFT
AWKIAKGLYLVPVLIAYTQLISWDVATVVTIGIFAIFGTYAMIGAIEGYLEGRLNLLWRL
LLAVIGVLLVWPSLPIWIRLVCVALFIAIFIYSGKTAARVERAHSAVRGAKSA