Protein Info for CSW01_14620 in Vibrio cholerae E7946 ATCC 55056

Annotation: type VI secretion protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 421 transmembrane" amino acids 203 to 224 (22 residues), see Phobius details PF06812: ImpA_N" amino acids 26 to 100 (75 residues), 33 bits, see alignment E=2.9e-12

Best Hits

KEGG orthology group: K11911, type VI secretion system protein VasL (inferred from 100% identity to vcm:VCM66_A0119)

Predicted SEED Role

"Type VI secretion-related protein VasL"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (421 amino acids)

>CSW01_14620 type VI secretion protein (Vibrio cholerae E7946 ATCC 55056)
MMSNVIFIDNVCYRLTNDSEEIRGLEPYAKVREEINRRFNPIAGGTDWAVVKEYCEQLAC
NQGMDFLICGYYAVACLKTQGLAGYATGMELMSASLANQGECDVKSAKVRKEILDWVNAR
VVQELKALKPTYESLRDLYRAERHCERLHQLFEQQQTEYKVDFEGVGFALFEHIDRIETQ
YHSLLKKQEKAQPPKLKFWQRGYALFTLGVLGVALGMVGGYWGWPWFYTTPYAAPQRITT
LNEASQTQALLNDSSTSERARWQHDLIPLYRDTLQQNLTISFSEPKRHAITQLNLLRTLY
PENEQVNALSQEFALQQQQALEQTALFVAKFSEIRTKMANISLLAKRGKWAELEKQTKSL
EEFAVSLSPIYGRVDYVQGLLEQGDVTNAQKEFAILKQRLDSLSWKIAELEQRIGDAALL
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