Protein Info for CSW01_14435 in Vibrio cholerae E7946 ATCC 55056

Annotation: MFS transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 403 transmembrane" amino acids 12 to 32 (21 residues), see Phobius details amino acids 49 to 69 (21 residues), see Phobius details amino acids 80 to 100 (21 residues), see Phobius details amino acids 109 to 126 (18 residues), see Phobius details amino acids 138 to 162 (25 residues), see Phobius details amino acids 168 to 188 (21 residues), see Phobius details amino acids 223 to 242 (20 residues), see Phobius details amino acids 254 to 274 (21 residues), see Phobius details amino acids 283 to 300 (18 residues), see Phobius details amino acids 307 to 331 (25 residues), see Phobius details amino acids 339 to 360 (22 residues), see Phobius details amino acids 371 to 389 (19 residues), see Phobius details PF07690: MFS_1" amino acids 24 to 203 (180 residues), 114.6 bits, see alignment E=2.4e-37 amino acids 225 to 387 (163 residues), 38.2 bits, see alignment E=4.3e-14

Best Hits

KEGG orthology group: None (inferred from 100% identity to vcj:VCD_000158)

Predicted SEED Role

"Multidrug resistance protein D"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (403 amino acids)

>CSW01_14435 MFS transporter (Vibrio cholerae E7946 ATCC 55056)
MNAQTSTRFRRTPMLLAMMIIATGQVGVSIYLPSLPLISRDLQVDQASAQMLVTLFLLGF
GGSQLFYGALSDAVGRRPTFLLGQGIYLLGTVLCVMMSDHFQALEFGRLLQGLGAGSASV
LGRSVLRDSYDGFHLTKALSYLSITASIMPIIAPVLGGWLAYHLSWQSVFIFVLLYIGAI
FTLGLMILPETLPYPKRRVQWRGIVINYAKLLTNQQVTSSASYNWLSYLASLVTLSILPF
LLQKQLGMTAADYGSTLIIPSSGLLLGSVLVNMLTSRFSVRQLLGCAISLMVFAGLWLLL
TEFSVFNLIWAFTWLSIAQGISFPLATTLLLSPHKSQAGAVSALSGSIQMGIAGLLGGYL
VEHWVTSQNAMGVFYILVGITMLSVLIATKKAHSQPSAAQVPM