Protein Info for CSW01_14385 in Vibrio cholerae E7946 ATCC 55056

Annotation: phosphate ABC transporter ATP-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 259 TIGR00972: phosphate ABC transporter, ATP-binding protein" amino acids 14 to 259 (246 residues), 417.5 bits, see alignment E=8e-130 PF00005: ABC_tran" amino acids 29 to 184 (156 residues), 108.4 bits, see alignment E=4.6e-35 PF13304: AAA_21" amino acids 139 to 214 (76 residues), 28.7 bits, see alignment E=1.5e-10

Best Hits

Swiss-Prot: 100% identical to PSTB2_VIBCH: Phosphate import ATP-binding protein PstB 2 (pstB2) from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)

KEGG orthology group: K02036, phosphate transport system ATP-binding protein [EC: 3.6.3.27] (inferred from 100% identity to vcj:VCD_000167)

MetaCyc: 53% identical to phosphate ABC transporter ATP binding subunit (Escherichia coli K-12 substr. MG1655)
ABC-27-RXN [EC: 7.3.2.1]; 7.3.2.1 [EC: 7.3.2.1]

Predicted SEED Role

"Phosphate transport ATP-binding protein PstB (TC 3.A.1.7.1)" in subsystem High affinity phosphate transporter and control of PHO regulon or Phosphate metabolism (TC 3.A.1.7.1)

MetaCyc Pathways

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.27

Use Curated BLAST to search for 3.6.3.27 or 7.3.2.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (259 amino acids)

>CSW01_14385 phosphate ABC transporter ATP-binding protein (Vibrio cholerae E7946 ATCC 55056)
MTEFRDNTMKTTKFNIENLDLFYGENQALKSINLPIPTRQVTALIGPSGCGKSTLLRCLN
RMNDLIEGVTITGKLTMDGQDVYGNIDVSDLRIRVGMVFQKPNPFPMSIYENVAYGLRAQ
GIKDKKHLDEVVERSLRGAALWDEVKDRLKSHAFGLSGGQQQRLCIARTIAMEPDVILMD
EPTSALDPIATHKIEELMEDLKKNYTIVIVTHSMQQARRISDRTAFFLMGELVEHDDTQV
IFSNPRDDRTRGYVNGDFG