Protein Info for CSW01_14335 in Vibrio cholerae E7946 ATCC 55056

Annotation: ATP-dependent helicase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 452 PF00270: DEAD" amino acids 29 to 199 (171 residues), 154.9 bits, see alignment E=2.6e-49 PF04851: ResIII" amino acids 32 to 194 (163 residues), 33.8 bits, see alignment E=4.8e-12 PF00271: Helicase_C" amino acids 237 to 345 (109 residues), 104.3 bits, see alignment E=6.7e-34

Best Hits

KEGG orthology group: None (inferred from 100% identity to vco:VC0395_0076)

Predicted SEED Role

"ATP-dependent RNA helicase VCA0061" in subsystem ATP-dependent RNA helicases, bacterial

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (452 amino acids)

>CSW01_14335 ATP-dependent helicase (Vibrio cholerae E7946 ATCC 55056)
MESTLQFKDLGLDNRLLKNLAHYNFKQATEIQQQAIPLTIAGRDLLASSKTGSGKTLAFV
LPMLHKSLKTKAFSAKDPRGLILVPTRELAKQVYGELRSMLGGLSYTATLITGGENFNDQ
VKALARGPRFIVATPGRLADHLDHRSLFLEGLETLVLDEADRMLDLGFAKELRRIHNAAK
HRRRQTLMFSATLDHADVNDMAMELLNEPKRIAIGVGSEEHKDITQHFYLCDHLDHKEAL
LDRILADAEYRQVIIFTATRADTDRLTEKLNQNNLKAVALSGNLNQTQRNTIMGQFERAV
FKILVTTDVASRGLDIPAVTHVINFDMPKHTEEYVHRVGRTGRAGNKGDAMSLVGPKDWE
SFKRVEAFLQQEIQFEVLAGLEGKFKGLKPRQAKPKAAPTQRVNKAKAPSKSKKAAPRDK
SFYQNVAVGDSVFIPKKKVAPKPEVDLEDDID