Protein Info for CSW01_14250 in Vibrio cholerae E7946 ATCC 55056

Annotation: DUF368 domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 308 transmembrane" amino acids 16 to 39 (24 residues), see Phobius details amino acids 71 to 95 (25 residues), see Phobius details amino acids 101 to 119 (19 residues), see Phobius details amino acids 130 to 149 (20 residues), see Phobius details amino acids 155 to 172 (18 residues), see Phobius details amino acids 178 to 196 (19 residues), see Phobius details amino acids 200 to 223 (24 residues), see Phobius details amino acids 229 to 246 (18 residues), see Phobius details amino acids 284 to 302 (19 residues), see Phobius details PF04018: VCA0040-like" amino acids 18 to 263 (246 residues), 350.7 bits, see alignment E=2.3e-109

Best Hits

KEGG orthology group: K08974, putative membrane protein (inferred from 100% identity to vcm:VCM66_A0039)

Predicted SEED Role

"Arginine/ornithine antiporter ArcD" in subsystem Arginine Deiminase Pathway or Arginine and Ornithine Degradation or Polyamine Metabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (308 amino acids)

>CSW01_14250 DUF368 domain-containing protein (Vibrio cholerae E7946 ATCC 55056)
MAGKTMNYLSTYLKGLAMGAADVVPGVSGGTIAFITGIYDTLLESIRRINPSLLKVWKAQ
GLAGVFRHINGLFLITLFGGIFTSIATLAKLISWLLVTHPIPIWSFFFGLILVSVWHMLR
QIEQKKLSRLLWLIAGAIFAYGITVLKPLHLEPTYINVLISGAIAICAMILPGISGSFIL
LLIGMYAPVLGAVKTFQLDILLIFLTGCVIGLLSFSHILSWLLRRYRDVTLTFLTGLMLG
TLPKIWPWKETLSWRVNSSGEQVPLLQRNLSPFEFETLTSQPSQWLLALVLMLAAVALVL
GLEKYAEK