Protein Info for CSW01_14095 in Vibrio cholerae E7946 ATCC 55056

Annotation: methyl-accepting chemotaxis protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 553 transmembrane" amino acids 9 to 29 (21 residues), see Phobius details amino acids 199 to 220 (22 residues), see Phobius details PF17200: sCache_2" amino acids 51 to 188 (138 residues), 100.8 bits, see alignment E=1.5e-32 PF08269: dCache_2" amino acids 77 to 186 (110 residues), 86.6 bits, see alignment E=3.4e-28 PF00672: HAMP" amino acids 220 to 272 (53 residues), 25.5 bits, see alignment 2.7e-09 PF00015: MCPsignal" amino acids 335 to 516 (182 residues), 134 bits, see alignment E=1e-42

Best Hits

Swiss-Prot: 39% identical to MALCR_PSEAE: Methyl-accepting chemotaxis protein PA2652 (PA2652) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)

KEGG orthology group: K03406, methyl-accepting chemotaxis protein (inferred from 100% identity to vch:VCA0008)

Predicted SEED Role

"Methyl-accepting chemotaxis protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (553 amino acids)

>CSW01_14095 methyl-accepting chemotaxis protein (Vibrio cholerae E7946 ATCC 55056)
MSLTIRQRLYILSLVPLLTIALSMMYFTFSETRLLSQEQMRNTREAMMEMKQAELKSYLQ
IADTALAPLKARQAPLDDAIAILREIQFGQSGYIFGYDSKGTRLLLGKATNGLGDNFMNM
QDTQGNYLIQDLLKNAKLNQFTTYYFPKPGEQTPLPKLSYSVYLPQWDLTIGTGFYTDDV
DAEIAEMEARAEEQLEQGLYTLAGITLLIVILVSVMAIMINRSIMRPLELFDNSISSFAS
GDADLTARMEKFSVPEFHKLSHNFNRFVESLQNIIKRVNQVGQQVVEETNAMSQRATQVD
HLASNQREETEQVATAMTEMTTTAQEISNNANNAAQSAKDAEDNATDVHNIVNAAARSVQ
ALAEEVADASSVIAKLEGDVNNITSSLAVIQDIAEQTNLLALNAAIEAARAGEQGRGFAV
VADEVRKLASRTQESTQQIHTMIQQLKAGSDAAVKAMESSQQRSITTVREANAAAEALQK
IQASIGTIMDMNALIATATEEQSIVGQEISQRIVVISDQSSESADLANQNRQGSQTLNGR
AHELYELVARFKV