Protein Info for CSW01_13735 in Vibrio cholerae E7946 ATCC 55056

Annotation: 3'(2'),5'-bisphosphate nucleotidase CysQ

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 275 TIGR01331: 3'(2'),5'-bisphosphate nucleotidase" amino acids 10 to 260 (251 residues), 373.7 bits, see alignment E=2.3e-116 PF00459: Inositol_P" amino acids 14 to 254 (241 residues), 181.4 bits, see alignment E=1.3e-57

Best Hits

Swiss-Prot: 46% identical to CYSQ_AGGAC: 3'(2'),5'-bisphosphate nucleotidase CysQ (cysQ) from Aggregatibacter actinomycetemcomitans

KEGG orthology group: K03677, CysQ protein (inferred from 100% identity to vcj:VCD_001645)

Predicted SEED Role

"3'(2'),5'-bisphosphate nucleotidase (EC 3.1.3.7)" (EC 3.1.3.7)

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.1.3.7

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (275 amino acids)

>CSW01_13735 3'(2'),5'-bisphosphate nucleotidase CysQ (Vibrio cholerae E7946 ATCC 55056)
MSTPQDLSHLLPDVINIARAAGQLILDIYQNKSYEAFTKSDSTPVTSADLAAHKFLCEQL
RELTPDIPILSEEEANIDLATRETWQRYWLVDPLDGTQEFIARSGDFATIIALVENNHPV
MGVVYGPVSGVTYYAYAGKGAWKIPDMAQSLKIQTHKHELPSSSIAIAISRRQDINKITR
RLSSAWNYDLVPLGSAALKACLVAEGAVDCYLRLGPTGEWDTAATQCIVEEAGGRILSTQ
LSPLSYNERETLENPNFIVLGDADLPWNEILKIKD