Protein Info for CSW01_13450 in Vibrio cholerae E7946 ATCC 55056

Annotation: EF-P beta-lysylation protein EpmB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 340 TIGR00238: KamA family protein" amino acids 5 to 328 (324 residues), 422.5 bits, see alignment E=1e-130 TIGR03821: EF-P beta-lysylation protein EpmB" amino acids 16 to 335 (320 residues), 519.1 bits, see alignment E=3.9e-160 PF13353: Fer4_12" amino acids 111 to 183 (73 residues), 29.8 bits, see alignment E=6.6e-11 PF04055: Radical_SAM" amino acids 116 to 231 (116 residues), 38.4 bits, see alignment E=1.5e-13

Best Hits

Swiss-Prot: 63% identical to EPMB_SALTY: L-lysine 2,3-aminomutase (epmB) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)

KEGG orthology group: None (inferred from 100% identity to vcm:VCM66_2581)

MetaCyc: 70% identical to lysine 2,3-aminomutase (Escherichia coli K-12 substr. MG1655)
5.4.3.-

Predicted SEED Role

"Lysyl-lysine 2,3-aminomutase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (340 amino acids)

>CSW01_13450 EF-P beta-lysylation protein EpmB (Vibrio cholerae E7946 ATCC 55056)
MPHIITRKVISVEQNWLQQLANAISDPLQLLQQLEIDPSPWQDGFEARKLFAQRVPQSFV
DRMQKGNPADPLLRQVLPLSAEFEIHPGYSHDPLDEQNNTVPGLLHKYKNRCLLIVKGGC
AINCRYCFRRHFPYEDNKGGKSAWQQSLDYIAQNPQLNEVIFSGGDPLMAKDHEIAWLME
RIAAIPHIKRLRIHSRLPVVIPARITDELVELFAQTRLQVLLVTHINHANEINLELKQQM
ARLRAVNVTLLNQGVLLKGVNDTVDAQVSLSETLFDAGILPYYLHVLDKVQGAAHFYVSD
DKARQIMAGLIEQVSGYLVPKLTREIGGRPSKTPLDLHLE