Protein Info for CSW01_13410 in Vibrio cholerae E7946 ATCC 55056

Annotation: protein-export protein SecB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 154 PF02556: SecB" amino acids 6 to 145 (140 residues), 189.2 bits, see alignment E=1.8e-60 TIGR00809: protein-export chaperone SecB" amino acids 9 to 146 (138 residues), 194.2 bits, see alignment E=4.8e-62

Best Hits

Swiss-Prot: 100% identical to SECB_VIBCM: Protein-export protein SecB (secB) from Vibrio cholerae serotype O1 (strain M66-2)

KEGG orthology group: K03071, preprotein translocase subunit SecB (inferred from 100% identity to vcj:VCD_001713)

Predicted SEED Role

"Protein export cytoplasm chaperone protein (SecB, maintains protein to be exported in unfolded state)"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (154 amino acids)

>CSW01_13410 protein-export protein SecB (Vibrio cholerae E7946 ATCC 55056)
MAEAAQAPQQQFAIQRIYLKDVSFEAPSSPVMFQKEWNPDVKLDLDTQSRELGQGVYEVV
LRLTVTVKNAEETAFLCEVQQAGIFSAEQMEAGQLAHCLGAFCPNILFPYARETISSLVV
KGTFPQLNLAPVNFDALFMNYLQQQAQEGATANA