Protein Info for CSW01_13385 in Vibrio cholerae E7946 ATCC 55056

Annotation: acetylornithine deacetylase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 378 TIGR01892: acetylornithine deacetylase (ArgE)" amino acids 8 to 372 (365 residues), 410.1 bits, see alignment E=4.3e-127 PF01546: Peptidase_M20" amino acids 72 to 374 (303 residues), 112.2 bits, see alignment E=3.4e-36 PF07687: M20_dimer" amino acids 174 to 285 (112 residues), 87.7 bits, see alignment E=4.9e-29

Best Hits

Swiss-Prot: 100% identical to ARGE_VIBCM: Acetylornithine deacetylase (argE) from Vibrio cholerae serotype O1 (strain M66-2)

KEGG orthology group: K01438, acetylornithine deacetylase [EC: 3.5.1.16] (inferred from 100% identity to vcm:VCM66_2565)

MetaCyc: 56% identical to acetylornithine deacetylase (Escherichia coli K-12 substr. MG1655)
Acetylornithine deacetylase. [EC: 3.5.1.16]

Predicted SEED Role

"Acetylornithine deacetylase (EC 3.5.1.16)" in subsystem Arginine Biosynthesis extended (EC 3.5.1.16)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.5.1.16

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (378 amino acids)

>CSW01_13385 acetylornithine deacetylase (Vibrio cholerae E7946 ATCC 55056)
MPLPSFLEVYEGLISTSSISSTDARWDEGNEQVIAKLADWLSALGFSIQIEQVAPNKQNL
IAKLGSGEGGLLLAGHSDTVPFDEGRWNYNPHALTQVNNRFYGLGTADMKGFFAFIYEAV
KNVDWSKQTKPLYVLATCDEETTMLGARHFTENAPFKPDYCIIGEPTSLVPIRAHKGHVA
NAIRVTGKSGHSSNPALGVNAIEIMHEVLFALMQLRDRLIKEYHHPGFEIPTPTLNLGHI
HGGDSPNRICGCCELHYDVRPLPGISLDGLDNLMHDALREVQQKWPGRIELVPLHDPIPG
YECAHDHPFIHGISEICEQEAQTVNYCTEAPFLQQVCPTLVLGPGSIDQAHQPDEFLAFE
FIDPTVRVLSRAMQKYCF