Protein Info for CSW01_13265 in Vibrio cholerae E7946 ATCC 55056

Annotation: nuclease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 869 signal peptide" amino acids 1 to 29 (29 residues), see Phobius details transmembrane" amino acids 845 to 865 (21 residues), see Phobius details PF00932: LTD" amino acids 25 to 134 (110 residues), 60 bits, see alignment E=2.7e-20 PF03372: Exo_endo_phos" amino acids 478 to 837 (360 residues), 25.1 bits, see alignment E=1.4e-09

Best Hits

KEGG orthology group: K07004, (no description) (inferred from 100% identity to vcj:VCD_001742)

Predicted SEED Role

"Extracellular deoxyribonuclease Xds"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (869 amino acids)

>CSW01_13265 nuclease (Vibrio cholerae E7946 ATCC 55056)
MEMRTTPNLTRSTLALAISFGLVAPSYADLLISQYVEGSSFNKAIEIANTSDQTVSLNGY
QLAMSTNGSGTWDKTLPLDGQVIAARDVLVIAHGSANSAILATADLTNNTVVNFNGNDPI
ALLNSDGSVHDVVGSMGGADFAKDNTLARTTLTPSATYQASDWATQGKDNIDGLGALDTT
TPPSAFNCTLDGAEPSFTTIQQIQGEGSTSPYIQGYPYITNEDFFVKGVVSAVTTGLTKG
FYLQSLEDDYNPNTSEGLFVFTNQSSSDLAPGDVVCVKGKVQEYYNLTQLKAENNQWVKQ
GQQAAPQAQAIEILPSDEHFAQTLERYEGMLVKTTPELDMRVTRTFGYDYASRRNNMVLA
QGRINMQPNQQHPAGSEQASQQKLDNAQRRLFVESDAKAPDGQIPYYPTFGRTDVDQDGS
TEDYIRIDDTVSGLEGVVSYSYNEYRLIVTNTISAENLVHNAPRQAKPDLDEGDLRIATF
NVLNYFNSPFGGDANQHGDNRGANNLAEFEVQQAKIVNAIVRLDADIVGLMEIENNGFGE
GSAIAQLVNQINSQIADKKKHYRFVAIDSNGDGKTDAADSLGTDVITTGVIYRDKVVKLA
QNRVIPMPSQQAPEVVDANGKVIEDGKNYQRDTLAPTFKVKGGNEKITVAVNHFKSKGSA
CWEDAAPVEQGGQAGKDLDYQGACENFRVAAAVALGDALAKIDGHKVILGDMNSYGMEDP
MLVLTDYTPEKYGKTIRAARNTYIAGLEQFGDAGAEIKHSYGYLNAVAMKHPDSWSYSFN
DEVGALDHLLVSPSLKHKVVDATDWHINGAESTLFDYNDEFKGNLPKYKDQFRASDHDPA
VLELNIYGGSLGLGALLGLLGLGVWRRRR